Results 41 to 50 of about 480,998 (248)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
A New Way to Store Simple Text Files
Algorithms, 2020 In the era of ubiquitous digitization, the Internet of Things (IoT), information plays a vital role. All types of data are collected, and some of this data are stored as text files.
Marcin Lawnik +2 more
doaj +1 more source
Indexing compressed text [PDF]
Journal of the ACM, 2005 We design two compressed data structures for the full-text indexing problem that support efficient substring searches using roughly the space required for storing the text in compressed form.Our first compressed data structure retrieves the occ occurrences of a pattern P [1, p
FERRAGINA, PAOLO, G. MANZINI
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Acoustic properties and low strain rate behavior of different types of chocolate
International Journal of Food Properties, 2023 Five different chocolate types (i.e. extra dark, dark, milk, white, and ruby) were characterized and compared for the acoustical and textural characteristics.
Šárka Nedomová +7 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Negative linear compressibility [PDF]
Physical Chemistry Chemical Physics, 2015 While all materials reduce their intrinsic volume under hydrostatic (uniform) compression, a select few actually expand along one or more directions during this process of densification.
Andrew B. Cairns, Andrew L. Goodwin
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Ceramics, 2023 In this work, composites based on AA5049 aluminium alloy reinforced with multiwalled carbon nanotubes (CNTs) and multiwalled TiC-coated CNTs were prepared by powder metallurgy.
Artemiy V. Aborkin +3 more
doaj +1 more source