Results 91 to 100 of about 1,759,868 (353)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Properties of two composite materials made of toughened epoxy resin and high-strain graphite fiber [PDF]
Results are presented from an experimental evaluation of IM7/8551-7 and IM6/18081, two new toughened epoxy resin, high strain graphite fiber composite materials.
Dow, Marvin B., Smith, Donald L.
core +1 more source
Numerical Model of CAI Test for Fibre-Reinforced Polymer Plate. [PDF]
, 2016 This article presents numerical simulations of laminates subjected to Compression After Impact (CAI) testing including delamination modelling. Different model of impact damages of laminate were considered.
Baszczyński, Piotr +3 more
core
Pain and analgesic use associated with skeletal-related events in patients with advanced cancer and bone metastases [PDF]
, 2015 PURPOSE: Bone metastases secondary to solid tumors increase the risk of skeletal-related events (SREs), including the occurrence of pathological fracture (PF), radiation to bone (RB), surgery to bone (SB), and spinal cord compression (SCC).
A Hussain +55 more
core +2 more sources
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Experimental study on impact and flexural behaviors of CFRP/aluminum-honeycomb sandwich panel
e-PolymersTo investigate the impact and flexure behavior of carbon fiber reinforced polymers/aluminum-honeycomb sandwich panel, low-velocity impact, compression-after-impact (CAI), and three-point flexure tests are conducted carefully.
Zhao Shicheng +5 more
doaj +1 more source
Impact testing to determine the mechanical properties of articular cartilage in isolation and on bone [PDF]
, 2009 The original publication is available at www.springerlink.comNon peer ...
A. ODGAARD +39 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Durability and damage tolerance of Large Composite Primary Aircraft Structure (LCPAS) [PDF]
Analysis and testing addressing the key technology areas of durability and damage tolerance were completed for wing surface panels. The wing of a fuel-efficient, 200-passenger commercial transport airplane for 1990 delivery was sized using graphite-epoxy
Mccarty, John E., Roeseler, William G.
core +1 more source