Results 41 to 50 of about 1,759,868 (353)

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

Influence of lightweight pumice on low velocity impact response of carbon fiber reinforced pumice epoxy core sandwich composites

Journal of Materials Research and Technology
The present study investigates novel carbon fiber sandwich composites reinforced with lightweight pumice. Four types of sandwich composites are manufactured by varying the pumice content in 0, 3, 6 and 9 wt%.
Imran Ibrahim Shaikh, Kiran Shahapurkar, Kiran MC, Venkatesh Chenrayan, Panneerselvam Natarajan, Vineet Tirth, Ali Algahtani, Amir Arabi, Vijayabhaskara Rao Bhaviripudi, Vasudevan Venkatachalam, Manzoore Elahi M. Soudagar, Andrey Pisarev, Muhammad Nasir Bashir, Joon Sang Lee, Shekhar Singh   +14 more
doaj   +1 more source

Edge impact modeling on stiffened composite structures [PDF]

, 2015
Finite Element Analysis of low velocity/low energy edge impact has been carried out on carbon fiber reinforced plastic structure. Edge impact experimental results were then compared to the numerical ‘‘Discrete Ply Model’’ in order to simulate the edge ...
Aboissière, Jacky, Bouvet, Christophe, Minot, Clément, Ostré, Benjamin   +3 more
core   +3 more sources

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser, Claire Laurie, Teresa Schmidt, Irene von Luettichau, Peter Bekkering, Sabine Kesting   +5 more
wiley   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source

Experiment and analysis of mechanical properties of carbon fiber composite laminates under impact compression

e-Polymers, 2022
Composite materials are more and more widely used in aircraft structural design, and impact damage is the most serious defect/damage form of aviation composite structures in service.
Yang Kang, Yang Li, Gong Peng, Zhang Liguo, Yue Yumei, Li Qunfang   +5 more
doaj   +1 more source

On the compact wave dynamics of tensegrity beams in multiple dimensions

, 2019
This work presents a numerical investigation on the nonlinear wave dynamics of tensegrity beams in 1D, 2D and 3D arrangements. The simulation of impact loading on a chain of tensegrity prisms and lumped masses allows us to apply on a smaller scale recent
Fraternali, Fernando, Micheletti, Andrea, Ruscica, Giuseppe   +2 more
core   +1 more source

Impact damage and CAI strength of a woven CFRP material with fire retardant properties [PDF]

, 2016
This paper presents the interrogation of low velocity impact and compression after impact test results on a woven fibre composite having a fire retardant, syntactic core, two phase epoxy matrix.
Abrate, ASTM D5528, ASTM D6671, ASTM D7136, ASTM D7137, Atas, Cantwell, Cytec Industrial Materials, Cytec Industrial Materials, Cytec Industrial Materials, Davies, Davies, Davies, Davies, DOT/FAA/AR-10/6, Efstathios E. Theotokoglou, Gerlach, Hancox, Ioannis K. Giannopoulos, Irving, Kim, Kim, Kuwata, Kuwata, Naik, Niu, Ogasawara, Olsson, Paris, Reddy, Richardson, Schoeppner, Seltzer, Siow, Vieille, Wang, Xiang Zhang, Zhang   +37 more
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Couple effects of multi-impact damage and CAI capability on NCF composites

Reviews on Advanced Materials Science
In this study, the mechanical properties of non-crimp fabric (NCF) composite laminates under low-velocity impact and compression after impact (CAI) tests were studied by Scanning electron microscopy (SEM) and Digital image correlation (DIC) techniques ...
Zhang Yuxuan, Yan Shi, Jiang Lili, Fan Tiancong, Zhai Junjun, Li Hanhua   +5 more
doaj   +1 more source