Results 61 to 70 of about 1,759,868 (353)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Experimental study on compression mechanical characteristics of filled rock joints after multiple pre-impacts

open access: yesScientific Reports, 2022
The prefabricated artificial filled jointed rock specimens are impacted by a self-made drop hammer impact device for many times, and the specimens with different degrees of cumulative damage characteristics are obtained.
Shaobo Chai   +4 more
doaj   +1 more source

Relationships between LRI process parameters and impact and post-impact behaviour of stitched and unstitched NCF laminates [PDF]

open access: yes, 2012
The general context of the development of out-of-autoclave processes in the aeronautics industry raises the question of the possible links between these new processes and impact behaviour. In this study, a Taguchi table was used in a design of experiment
Berthet, Florentin   +3 more
core   +3 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Experimental damage tolerance evaluation of thick fabric carbon/epoxy laminates under low-velocity and high-velocity impact and compression-after-impact

open access: yesJournal of composite materials, 2022
Impact experiments of thick fabric carbon/epoxy laminate specimens, with small thickness ratio, are conducted at distinct energy levels and thicknesses to characterise the damage process. These specimens and loading conditions are representative of a new
Niels van Hoorn   +3 more
semanticscholar   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

A novel approach to estimation of residual strength of laminated polymer composites under compression after impact

open access: yesFracture and Structural Integrity
This work is dedicated to the experimental study of the influence of preliminary dynamic loading on the residual strength of the laminated polymer composite under compression.
Oleg Staroverov   +3 more
doaj   +1 more source

Strength of multilayered plates with impact damage

open access: yesУчёные записки Казанского университета: Серия Физико-математические науки, 2022
This article solves one of the central problems of how impact damage affects the strength of polymer composite materials (PCM). Impact damage on sandwich materials varies in the resulting shape and size, thus hampering the numerical assessment of their ...
V.I. Mitryaykin, O.N. Bezzametnov
doaj  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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