Results 81 to 90 of about 1,759,868 (353)

Compressible Air Entrapment in High-Speed Drop Impacts on Solid Surfaces

open access: yes, 2012
Using high-speed photography coupled with optical interference, we experimentally study the air entrapment during a liquid drop impacting a solid substrate.
Liu, Yuan, Tan, Peng, Xu, Lei
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Fatigue Performance of Composite Laminates After Low-velocity Impact

open access: yesCailiao gongcheng, 2016
Compression-compression fatigue tests were carried out on T300/5405 composite laminates after low-velocity impact, compression performance of the laminates with different impact damages was studied together with its fatigue life and damage propagation ...
LIANG Xiao-lin, XU Xi-wu, LIN Zhi-yu
doaj   +1 more source

The linearity response of the Planck-LFI flight model receivers [PDF]

open access: yes, 2009
In this paper we discuss the linearity response of the Planck-LFI receivers, with particular reference to signal compression measured on the 30 and 44 GHz channels.
A Gregorio   +53 more
core   +2 more sources

Experimental Investigation on Low-velocity Impact and Compression After Impact Properties of Three-dimensional Five-directional Braided Composites

open access: yesCailiao gongcheng, 2017
The low-velocity impact and compression after impact (CAI) properties of three-dimensional (3D) five-directional carbon fiber/epoxy resin braided composites were experimentally investigated.
YAN Shi   +4 more
doaj   +1 more source

Properties of three graphite/toughened resin composites [PDF]

open access: yes
Results are presented from an experimental evaluation of IM7/977-2, IM7/F655, and T800/F3900. Data presented include ply-level (unidirectional laminate) strength and moduli, unnotched and notched (open hole) tension and compression properties of quasi ...
Dow, Marvin B., Smith, Donald L.
core   +1 more source

Experimental analysis of impact and post-impact behaviour of inserts in Carbon sandwich structures [PDF]

open access: yes, 2019
In aeronautics, honeycomb sandwich structures are widely used for secondary structures such as landing gear doors, flaps or floors, and for primary structures in helicopters or business jets.
Bouvet, Christophe   +5 more
core   +3 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

X-ray microtomographic characterization and quantification of the strain rate dependent failure mechanism in cenosphere epoxy syntactic foams [PDF]

open access: yes, 2016
This work investigates the failure mechanism in cenosphere epoxy syntactic foams at the quasi-static and dynamic strain rates. Split-Hopkinson pressure bar experiments are controlled to stop dynamic deformation of the foams at various strain stages.
Adrien   +26 more
core   +1 more source

Home - About - Disclaimer - Privacy