Results 101 to 110 of about 5,883,031 (297)

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Chemical Characterisation of Compression Wood in Plantation Grown Pinus Radiata [PDF]

open access: yes, 2007
The primary objective of this study was to find out if changes in chemistry could be used to quantify Pinus radiata compression wood severity or degree of compression wood development.
Nanayakkara, Bernadette
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

A Compression-Driven Test Access Mechanism Design Approach

open access: yes, 2004
Driven by the industrial need for low-cost test methodologies, the academic community and the industry alike have put forth a number of efficient test data compression (TDC) methods. In addition, the need for core-based System-on-a-Chip (SoC) test led to
Gonciari, Paul Theo, Al-Hashimi, Bashir
core   +1 more source

Damage Analysis of a Ferritic SiMo Ductile Cast Iron Submitted to Tension and Compression Loadings in Temperature

open access: yesMetals, 2015
Tensile and compression tests were carried out on a ductile cast iron for temperatures up to 1073 K. The damage caused inside and around graphite nodules was evaluated as a function of the local equivalent plastic strain by using microstructural ...
Isabel Hervas, Anthony Thuault, Eric Hug
doaj   +1 more source

A Distinguisher for the Compression Function of SIMD-512 [PDF]

open access: yes, 2009
SIMD is one of the round 2 candidates of the public SHA-3 competition hosted by NIST. It was designed by Leurent et al.. In this paper, we present a distinguisher attack on the compression function of SIMD-512. By linearizing the compression function we construct a linear code.
Florian Mendel, Tomislav Nad
openaire   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Accounting for the Inhomogeneity of Deformation in Identification of Microstructure Evolution Model / Niejednorodność Odkształcenia W I Dentyfikacji Modelu Rozwoju Mikrostruktury

open access: yesArchives of Metallurgy and Materials, 2015
The paper deals with the problem of identification of microstructure evolution model on the basis of two-step compression test. Classical interpretation of this test assumes uniform fields of strains, stresses and temperatures in the deformation zone and
Szeliga D.   +4 more
doaj   +1 more source

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