Results 81 to 90 of about 250,620 (292)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Compressive Sensing via Nonlocal Smoothed Rank Function

open access: yesPLOS ONE, 2016
Compressive sensing (CS) theory asserts that we can reconstruct signals and images with only a small number of samples or measurements. Recent works exploiting the nonlocal similarity have led to better results in various CS studies. To better exploit the nonlocal similarity, in this paper, we propose a non-convex smoothed rank function based model for
Ya-Ru Fan   +3 more
openaire   +4 more sources

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Damage Analysis of a Ferritic SiMo Ductile Cast Iron Submitted to Tension and Compression Loadings in Temperature

open access: yesMetals, 2015
Tensile and compression tests were carried out on a ductile cast iron for temperatures up to 1073 K. The damage caused inside and around graphite nodules was evaluated as a function of the local equivalent plastic strain by using microstructural ...
Isabel Hervas, Anthony Thuault, Eric Hug
doaj   +1 more source

Weaknesses in the HAS-V Compression Function [PDF]

open access: yes, 2007
HAS-V is a cryptographic hash function which processes 1024-bit message blocks and produces a hash value of variable length. The design of the hash function is based on design principles of the MD4 family. Recently, weaknesses have been shown in members of this family. Therefore, the analysis of the HAS-V hash function is of great interest. To the best
Mendel, Florian, Rijmen, Vincent
openaire   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Accounting for the Inhomogeneity of Deformation in Identification of Microstructure Evolution Model / Niejednorodność Odkształcenia W I Dentyfikacji Modelu Rozwoju Mikrostruktury

open access: yesArchives of Metallurgy and Materials, 2015
The paper deals with the problem of identification of microstructure evolution model on the basis of two-step compression test. Classical interpretation of this test assumes uniform fields of strains, stresses and temperatures in the deformation zone and
Szeliga D.   +4 more
doaj   +1 more source

The efficacy of intermittent pneumatic compression and negative pressure therapy on muscle function, soreness and serum indices of muscle damage: a randomized controlled trial [PDF]

open access: gold, 2021
Szczepan Wiecha   +9 more
openalex   +1 more source

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