Results 91 to 100 of about 6,136,545 (253)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

The impact of chest compression rates on quality of chest compressions : a manikin study [PDF]

, 2011
Purpose Chest compressions are often performed at a variable rate during cardiopulmonary resuscitation (CPR). The effect of compression rate on other chest compression quality variables (compression depth, duty-cycle, leaning, performance decay over ...
Field, Richard A., Akhtar, Naheed, Jasmeet Soar, Naheed Akhtar, Soar, Jasmeet, Davies, Robin P., Robin P. Davies, Perkins, Gavin, Akhtar, N, Perkins, Gavin D., Soar, J, Field, Richard A, Field, RA, Perkins, Gavin D, Davies, RP, Davies, Robin P, Gavin D. Perkins, Richard A. Field   +17 more
core   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Metrics for Stereoscopic Image Compression [PDF]

, 2012
Metrics for automatically predicting the compression settings for stereoscopic images, to minimize file size, while still maintaining an acceptable level of image quality are investigated.
GORLEY, PAUL,WARD, Gorley, Paul Ward
core  

Designing lightweight 3D-printable bioinspired structures for enhanced compression and energy absorption properties [PDF]

Recent progress in additive manufacturing, also known as 3D printing, has offered several benefits, including high geometrical freedom and the ability to create bioinspired structures with intricate details.
El-Sayed, M., A. Alsaleh, N., Harish, A., Essa, K., Ahmadein, M., Elfar, A., Hassanin, H., Djuansjah, J.   +7 more
core   +1 more source

Influence of Moisture Content on Some Elastic Constants of Black Pine Subjected to Compression [PDF]

Pro Ligno, 2017
Moisture content is an important factor influencing physical and mechanical behaviors of wood materials. This research aimed at quantifying effect of moisture content on some orthotropic mechanical properties of Black pine wood.
Ergun GUNTEKIN, Seda DEMIRATLI
doaj  

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Comparison of the effect of locking vs standard screws on the mechanical properties of bone-plate constructs in a comminuted diaphyseal fracture model [PDF]

, 2012
The purpose of this study was to compare the mechanical properties of bone-plate constructs with locking compression plates (LCP) used either with standard screws or with locking screws on an experimental model of comminuted ...
Autefage, André, Palierne, Sophie, Verset, Michaël, Swider, Pascal, Mathon, Didier   +4 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Contribution of postnatal collagen reorientation to depth-dependent mechanical properties of articular cartilage [PDF]

, 2011
The collagen fibril network is an important factor for the depth-dependent mechanical behaviour of adult articular cartilage (AC). Recent studies show that collagen orientation is parallel to the articular surface throughout the tissue depth in perinatal
Kranenbarg, S., Turnhout, M.C., van, Leeuwen, J.L., van   +2 more
core   +1 more source