Results 31 to 40 of about 871,514 (303)
Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack +12 more
wiley +1 more source
Biaxial compression test technique [PDF]
, 1975 Fixture and technique have been developed for predicting behavior of stiffened skin panels under biaxial compressive loading. Tester can load test panel independently in longitudinal and transverse directions.
Hansard, E. T.
core +1 more source
Group testing for image compression [PDF]
Proceedings DCC 2000. Data Compression Conference, 2002 This paper presents Group Testing for Wavelets (GTW), a novel embedded-wavelet-based image compression algorithm based on the concept of group testing. We explain how group testing is a generalization of the zerotree coding technique for wavelet-transformed images. We also show that Golomb coding is equivalent to Hwang's group testing algorithm. GTW is
Edwin S, Hong, Richard E, Ladner
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser +5 more
wiley +1 more source
Data compression by a decreasing slope-threshold test [PDF]
, 1973 Resolution can be obtained at large compression ratios with method for selecting data points for transmission by telemetry in television compressed-data system. Test slope of raw data stream and compare it to symmetric pair of decreasing thresholds. When
Kleinrock, L.
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou +10 more
wiley +1 more source
Study of tensile strength and compression strength of binary polymeric blends (High Density poly ethylene /polycarbonate) [PDF]
Engineering and Technology Journal, 2008 In this work, HDPE/PC binary polymeric blends has been made by using the singlescrew extruder machine .The tensile strength measurements showed that this blend have higherresults reflects the homogeneity of the mixture and higher strengthcompared with ...
Sanaa A. Hafad +2 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Metals, 2020 Severe plastic deformation (SPD) can fabricate high-strength materials by forming an ultrafine grained (UFG) microstructure. Low elongation to failure of UFG materials in tensile tests, which has often been regarded as a measure of ductility of materials,
Mayu Asano +5 more
doaj +1 more source