Results 41 to 50 of about 7,612,198 (301)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

A Compression-Driven Test Access Mechanism Design Approach

open access: yes, 2004
Driven by the industrial need for low-cost test methodologies, the academic community and the industry alike have put forth a number of efficient test data compression (TDC) methods. In addition, the need for core-based System-on-a-Chip (SoC) test led to
Gonciari, Paul Theo, Al-Hashimi, Bashir
core   +1 more source

Comparison of The Mechanical Properties of Low-Cost Bio Fiber Reinforced Polymer Composites

open access: yesInternational Journal of Applied Mechanics and Engineering
In this study, the physical, and mechanical properties of low-cost and biocomposites were evaluated. The walnut shell and date palm frond fibers were thermally treated in an oven at a temperature of 70°C and then chemically treated with NaOH and ...
Sanad Abdulkareem Ismael   +1 more
doaj   +1 more source

Potential of High Compressive Ductility of Ultrafine Grained Copper Fabricated by Severe Plastic Deformation

open access: yesMetals, 2020
Severe plastic deformation (SPD) can fabricate high-strength materials by forming an ultrafine grained (UFG) microstructure. Low elongation to failure of UFG materials in tensile tests, which has often been regarded as a measure of ductility of materials,
Mayu Asano   +5 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Experimental study on normal deformation characteristics of filled rock joints with typical fluctuation morphology

open access: yesFrontiers in Earth Science, 2023
The uneven deformation of filled rock joints subjected to ground stress can easily cause instability in engineering rock masses. Fluctuations in morphology and filling are the main factors affecting the normal deformation of filled rock joints.
Zhanyou Luo   +6 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

COMPRESSION TESTING OF ORANGE FRUITS

open access: yesChemical Engineering Transactions, 2009
Not available.
Federico Pallottino   +3 more
openaire   +2 more sources

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

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