Results 61 to 70 of about 316,051 (313)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Simulação computacional aplicada ao desenvolvimento de embalagens para bananas Computational simulation for the development of packages for bananas

open access: yesRevista Brasileira de Fruticultura, 2008
Este trabalho propõe um método de projeto de embalagem para produtos hortícolas, buscando uma otimização integrada dos aspectos geométricos, estruturais e térmicos, ligados à facilitação do resfriamento e armazenamento refrigerado. Para o dimensionamento
Roberto Funes Abrahão   +2 more
doaj   +1 more source

Mechanical response of shape-recovering metamaterial structures fabricated by additive manufacturing

open access: yesMaterials Research Express, 2021
Three different metamaterial structures were fabricated using stereolithography 3D printing and a shape recovering material. Mechanical properties and recovery efficiency were assessed after compression testing.
Md Sahid Hassan   +5 more
doaj   +1 more source

Compression test setup.

open access: yes, 2022
Compression test setup.
John Botsis (12511600)   +9 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Johnson-Cook model for TC4 titanium alloy based on compression experiment

open access: yesMetalurgija, 2022
To obtain the exact mechanical properties of TC4 titanium alloy, the compression experiments on TC4 titanium alloy at different strain rates (10-2,10-3,10-4 s-1) were performed at room-temperature on the MTS-810 electrohydraulic servo material testing ...
Z. L. Zhao   +4 more
doaj  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Partical shape evaluation before and after compression / Atskirų grunto dalelių formos kitimas prieš ir po spūdumo bandymo

open access: yesMokslas: Lietuvos Ateitis, 2012
The paper investigates typical Baltic sea-shore sand along Klaipėda and diagnoses the level of particle crushing after different loading steps. An oedometer test is done applying to drained loose (e0 = 0,764) and dense (e0 = 0,604) sand. The used loading
Šarūnas Skuodis, Agata Kavrus
doaj   +1 more source

A Compression-Driven Test Access Mechanism Design Approach

open access: yes, 2004
Driven by the industrial need for low-cost test methodologies, the academic community and the industry alike have put forth a number of efficient test data compression (TDC) methods. In addition, the need for core-based System-on-a-Chip (SoC) test led to
Gonciari, Paul Theo, Al-Hashimi, Bashir
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

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