Results 41 to 50 of about 1,054,579 (292)
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani +7 more
wiley +1 more source
Portfolio Selection by Compromise Programming
[EN] CP is a deterministic model like WGP in this aspect. Therefore, CP seems inappropriate to select stock portfolios from the Eu(R) maximization theory. In contrast to MV-SGP model, CP does not generalize Markowitz M-V model to multiple objectives.
Ballestero, Enrique +3 more
openaire +2 more sources
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A Nadir Compromise Programming for Supplier Selection Problem under Uncertainty
Supplier selection is one of the influential decisions for effectiveness of purchasing and manufacturing policies under competitive conditions of the market.
Mostafa Ekhtiari +3 more
doaj +2 more sources
A new multi‐criteria framework to identify optimal detention ponds in urban drainage systems
Urban development broadly impacts the hydrological cycle, leading to increased peak flow and flooding. Surface water detention ponds are among the most efficient measures for attenuating peak flow and returning it from development to pre‐development ...
Azadeh Hosseinzadeh +5 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
A Compromise Solution for the Fully Fuzzy Multiobjective Linear Programming Problems
A new approach is undertaken to solve the fully fuzzy multiobjective linear programming (FFMLP) problem. The coefficients of the objective functions, constraints, right-hand-side parameters, and variables are of the triangular fuzzy number (TrFN)s.
Abdulqader Othman Hamadameen +1 more
doaj +1 more source
Computing efficient financial strategies: An extended compromise programming approach [PDF]
This paper proposes a mathematical model to plan the financial strategy of a large company. The model links the philosophy of new behavioural economics with the multiple criteria decision making paradigm. Within this theoretical approach, the proposed model is supported by more realistic behavioral hypotheses.
Martin Valmayor, Miguel Angel +2 more
openaire +3 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source

