Living with the Unknown: Intolerance of Uncertainty in Parkinson's Disease
Abstract Background Parkinson's disease (PD) is marked by pervasive uncertainty due to fluctuating motor and non‐motor symptoms, variable treatment response, and an unpredictable clinical course. Intolerance of uncertainty (IU), a tendency to perceive ambiguity as threatening and respond with worry, avoidance, or decisional paralysis, may be ...
Bradley McDaniels +3 more
wiley +1 more source
Pharmacotherapy for online behavioral addictions: a systematic review. [PDF]
Park JJ, Chen BB, Potenza MN.
europepmc +1 more source
Virtual Reality-Delivered Exposure for Contamination Concerns in Adults With Obsessive-Compulsive Symptoms: Single-Arm Pilot Study. [PDF]
Caltabiano A +6 more
europepmc +1 more source
Distinct Brain Drivers and Shared Cerebello–Cortical Input in ADCY5 and SGCE Hyperkinetic Movements
Resting‐state fMRI and effective connectivity revealed distinct cerebellar–basal ganglia–cortical interactions in ADCY5 (MxMD‐ADCY5) and SGCE (MYC/DYT‐SGCE) related movement disorders. The cerebellum modulated cortex directly in MYC/DYT‐SGCE, but indirectly via basal ganglia‐cerebellar projections in MxMD‐ADCY5, which also showed reduced subthalamic ...
Clément Tarrano +33 more
wiley +1 more source
Measuring Cognitive Flexibility in Chinese Individuals with Obsessive-Compulsive Disorder: Psychometric Validation and Factor Structure of the Chinese Version of the Flexibility in Daily Life Scale. [PDF]
Yan Z, Chen T, Ma X, Mi S, Wang P, Li Z.
europepmc +1 more source
Clinical Predictors of Tic‐Related Impairment in Children and Adults with Tourette Syndrome
Abstract Background Tic‐related impairment drives treatment decisions for Tourette syndrome and related tic disorders. The clinical features most strongly associated with impairment remain unclear. Objective The aim of this analysis is to identify clinical predictors of tic‐related impairment in children and adults with tic disorders in a prospective ...
Wm. Jeptha Davenport +4 more
wiley +1 more source
Cognitive and emotional traits as mediators in the relationship between family factors and obsessive-compulsive disorder in adolescents. [PDF]
Lei M +7 more
europepmc +1 more source
Abstract Background There is a lack of treatments for non‐motor symptoms (NMS) in Parkinson's disease (PD). Objective To assess the safety and effectiveness of an oral Cannabis sativa L. extract on pain and other NMS of PD. Methods This phase II, randomized, placebo‐controlled trial evaluated a formulation containing cannabidiol (CBD; 96 mg/ml) and Δ9 ...
Gabriel T. Kubota +14 more
wiley +1 more source
Validation of a Low-Burden, Once-Daily Obsessive-Compulsive Disorder Measure Over 70 Days: Ecological Momentary Assessment Study. [PDF]
Jiang A, Li R, Fan J, Frank AC.
europepmc +1 more source
Apathy in Lewy Body Disorders: A Position Paper
Abstract Apathy is one of the most prevalent and disabling non‐motor symptoms in Parkinson's disease (PD) and dementia with Lewy bodies (DLB), collectively referred to as Lewy body disorders (LBDs). It is associated with reduced quality of life, accelerated cognitive decline, increased caregiver burden, and poorer functional outcomes, yet remains ...
Jaime Kulisevsky +12 more
wiley +1 more source

