Results 41 to 50 of about 223,654 (287)

Regulation of the Structure of the Insurance Portfolio as a Mechanism to Reduce the Risks of Insurance Companies

open access: yesМир новой экономики, 2018
The purpose of this article is to determine the influence of the portfolio structure on the stability of insurance companies’ activity. With this objective, we examined how the structure of insurance portfolio affects the risks of companies’ activity.The
A. V. Larionov
doaj   +1 more source

What helps and hinders doctors in engaging in continuous professional development? An explanatory sequential design.

open access: yesPLoS ONE, 2020
BackgroundLicensure and registration are the traditional approaches to ensure minimally acceptable standards of care for practice. However, due to advances in medical technology and changes in clinical practice, the knowledge and skills obtained from ...
Carrie H K Yam   +2 more
doaj   +1 more source

Compulsory Licensing Issues and Trends in Asia [PDF]

open access: yesPharmaceutical Patent Analyst, 2013
*Tilleke & Gibbins International Ltd., Supalai Grand Tower, 26th Floor 1011 Rama 3 Road, Chongnonsi, Yannawa, Thailand Tel.: +66 2653 5874 E-mail: siraprapha.r@tilleke.com Government-use compulsory licensing has almost always stirred up controversies and debates with regard to its appropriateness, actual benefits and detriments.
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

An assessment of prominent proposals to amend intellectual property regimes using a human rights framework

open access: yesLa Propiedad Inmaterial, 2014
A wide range of proposals to alleviate the negative effects of intellectual property regimes is currently under discussion. This article offers a critical evaluation of six of these proposals: the Health Impact Fund, the Access to Knowledge movement ...
Cristian Timmermann
doaj   +2 more sources

INDONESIA GOVERNMENT GRANTED 7 COMPULSORY LICENCES TO PROMOTE ACCES TO HIV RELATED MEDICINES

open access: yesVitae, 2013
“Starting with Malaysia in 2003, many Asian countries are now taking action to promote cheaper medicines through compulsory licensing, with Indonesia being the most recent case.
Germán Velásquez
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Access to hepatitis C virus treatment: Lessons from implementation of strategies for increasing access to antiretroviral treatment

open access: yesInternational Journal of Infectious Diseases, 2018
At September’s 2017 United Nations General Assembly, a state-of-the-art HIV medicine was announced to be made available at just $75 per person per year. There have been a number of strategies that the global AIDS community and countries have utilized to ...
Yibeltal Assefa   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Development of legislation of Ukraine on compulsory licenses for inventions (useful models) [PDF]

open access: yes, 2019
У статті досліджувалися теоретичні питання щодо становлення та розвитку інституту примусових ліцензій на винахід (корисну модель). Здійснено аналіз законодавства щодо регулювання цих відносин.
Юрків, Р. О.
core   +1 more source

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