Results 41 to 50 of about 3,156 (249)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Access to hepatitis C virus treatment: Lessons from implementation of strategies for increasing access to antiretroviral treatment

International Journal of Infectious Diseases, 2018
At September’s 2017 United Nations General Assembly, a state-of-the-art HIV medicine was announced to be made available at just $75 per person per year. There have been a number of strategies that the global AIDS community and countries have utilized to ...
Yibeltal Assefa, Peter S. Hill, Owain D. Williams   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Zadania inwestycyjne jednostek samorządu terytorialnego województwa lubelskiego w zakresie ochrony zdrowia = Investment projects of local government units in the province of Lublin about health care

Journal of Education, Health and Sport, 2016
Warchoł Martyna, Furtak-Niczyporuk Marzena, Pachuta Małgorzata. Zadania inwestycyjne jednostek samorządu terytorialnego województwa lubelskiego w zakresie ochrony zdrowia = Investment projects of local government units in the province of Lublin about ...
Martyna Warchoł, Marzea Furtak-Niczyporuk, Małgorzata Pachuta   +2 more
doaj   +3 more sources

Current Problems of International Legal Copyright Protection

Теоретическая и прикладная юриспруденция
The article examines the level of international copyright protection from the perspective of such aspects as the urgent nature of copyright protection and the possibility of applying the institution of compulsory license.
L. V. Shvarts, S. M. Burova
doaj   +1 more source

The evolution of the national licensing system of health care professionals: a qualitative descriptive case study in Lao People’s Democratic Republic

Human Resources for Health, 2017
Background The introduction of a systematic framework for the licensing of health care professions, which is a crucial step in ensuring the quality of human resources for health (HRH), is still evolving in Lao People’s Democraic Republic. The aim of this
Miwa Sonoda, Bounkong Syhavong, Chanphomma Vongsamphanh, Phisith Phoutsavath, Phengdy Inthapanith, Arie Rotem, Noriko Fujita   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A socially just pedagogy in the use of mobile devices in higher education? The case of Humanities first-year students at a South African university

SOTL in the South, 2018
In a highly unequal society such as South Africa, higher education is seen as having a social justice mandate to widen participation, and using technology is one way to achieve this.
Carina van Rooyen, Ingrid Estha Marais
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source