Results 61 to 70 of about 223,654 (287)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Statistic Analysis of Bank Deposit Insurance System in the Russian Federation
Вестник Российского экономического университета имени Г. В. ПлехановаIn the last decade in crisis conditions of country economy, withdrawal of licenses of many commercial banks due to deterioration of their finance standing and low confidence of people to the banking system because of insufficient finance literacy the ...
E. V. Lapteva
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Ius et Praxis, 2010 En la implementación de sus múltiples acuerdos internacionales en materia de propiedad intelectual, Chile ha modificado su Ley de Propiedad Industrial, la cual reglamenta el sistema de patentes, reconociendo la patentabilidad de productos farmacéuticos ...
Alberto Cerda Silva
doaj
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Television Satellite and Cable Retransmission of Broadcast Video Programming Under the Copyright Act’s Compulsory Licenses [PDF]
, 1998 This report reviews the history and background of the cable and television satellite licenses of the Copyright Act, reviews the Satellite Home Viewer Act of 1994, and notes recent developments, including: the 1997 satellite license rate adjustment ...
Schrader, Dorothy
core
Science-based health innovation in Uganda: creative strategies for applying research to development
BMC International Health and Human Rights, 2010 Background Uganda has a long history of health research, but still faces critical health problems. It has made a number of recent moves towards building science and technology capacity which could have an impact on local health, if innovation can be ...
Daar Abdallah S +4 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Infographic: Driver's licenses for all - the key to safety and security in Pennsylvania
, 2015 Temple University. James E. Beasley School of LawThis fact sheet reproduces key figures, findings, and recommendations from the Sheller Center Report, Drivers Licenses for All: The Key to Safety and Security in ...
Dragalin, Michaela +3 more
core +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source