Results 61 to 70 of about 91,806 (295)

Policies and programs to facilitate access to targeted cancer therapies in Thailand.

open access: yesPLoS ONE, 2015
BackgroundIncreasing access to clinically beneficial targeted cancer medicines is a challenge in every country due to their high cost. We describe the interplay of innovative policies and programs involving multiple stakeholders to facilitate access to ...
Rosarin Sruamsiri   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Stay Tuned: Whether Cloud-Based Service Providers Can Have Their Copyrighted Cake and Eat It Too [PDF]

open access: yes, 2014
Copyright owners have the exclusive right to perform their works publicly and the ability to license their work to others who want to share that right. Subsections 106(4) and (5) of the Copyright Act govern this exclusive public performance right, but
Asaro, Amanda
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Statistic Analysis of Bank Deposit Insurance System in the Russian Federation

open access: yesВестник Российского экономического университета имени Г. В. Плеханова
In the last decade in crisis conditions of country economy, withdrawal of licenses of many commercial banks due to deterioration of their finance standing and low confidence of people to the banking system because of insufficient finance literacy the ...
E. V. Lapteva
doaj   +1 more source

Impact of Global Patent and Regulatory Reform on Patent Strategies for Biotechnology [PDF]

open access: yes, 2009
I come to you this morning not as an intellectual property lawyer but as a former general counsel of biotechnology and pharmaceutical related companies, as an attorney with significant exposure to intellectual property issues and as one who has seen ...
Napoleon, Vincent J.
core   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

LICENCIAS OBLIGATORIAS POR RAZONES DE SALUD PÚBLICA EN CHILE: UN ANÁLISIS COMPARATIVO CON EL ACUERDO SOBRE LOS ADPIC Compulsory licenses for reasons of public health in Chile: a comparative analysis with the trips agreement

open access: yesIus et Praxis, 2010
En la implementación de sus múltiples acuerdos internacionales en materia de propiedad intelectual, Chile ha modificado su Ley de Propiedad Industrial, la cual reglamenta el sistema de patentes, reconociendo la patentabilidad de productos farmacéuticos ...
Alberto Cerda Silva
doaj  

Science-based health innovation in Uganda: creative strategies for applying research to development

open access: yesBMC International Health and Human Rights, 2010
Background Uganda has a long history of health research, but still faces critical health problems. It has made a number of recent moves towards building science and technology capacity which could have an impact on local health, if innovation can be ...
Daar Abdallah S   +4 more
doaj   +1 more source

Under a cloud of uncertainty: Legal questions affecting Internet storage and transmission of copyright-protected video content

open access: yes, 2016
The rapid growth of multimedia consumption has triggered technical, economic, and business innovations that improve the quality and accessibility of content. It has also opened new markets, promising large revenues for industry players.
Fund, Fraida   +2 more
core   +1 more source

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