Results 71 to 80 of about 223,654 (287)

Compulsory licenses and copyright

open access: yes, 2014
Defende a compatibilidade de licenças compulsórias com o ordenamento jurídico brasileiro e indica hipóteses em que esse instituto poderia ser implementado no Brasil.
Leonardi, Fernanda Stinchi Pascale
core  

Ethnic variations in compulsory detention and hospital admission for psychosis across four UK Early Intervention Services [PDF]

open access: yes, 2014
Substantial ethnic variations have been found in incidence, pathways to care and outcomes in psychosis. It is unknown whether these remain as marked in the presence of specialist Early Intervention Services (EIS) for psychosis.
Barnaby Major   +23 more
core   +2 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Forced to be Rich? Returns to Compulsory Schooling in Britain [PDF]

open access: yes
Do students benefit from compulsory schooling? In an important article, Oreopoulos (2006) studied the 1947 British compulsory schooling law change and found large returns to schooling of about 15% using the General Household Survey (GHS).
Paul J. Devereux, Robert A. Hart
core   +2 more sources

Licenses

open access: yes, 2018
Presentation slides for the training seminar about Licenses in Research Data Management of the FoDaKo-project: https://fodako.de English full text version: https://doi.org/10.5281/zenodo.1463156 German full text version: https://doi.org/10.5281/zenodo ...
Rathmann, Torsten (5890868)   +1 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Package Bidding for Spectrum Licenses [PDF]

open access: yes
The FCC was an innovator in adopting the rules of the simultaneous ascending-price auction for its sales of spectrum licenses. While these rules have performed well in the auctions conducted so far (and would perform even better with the design ...
Bradley Miller   +6 more
core  

La santé globale : biopolitique en territoires

open access: yesRevue Francophone sur la Santé et les Territoires, 2018
The 1851 Paris Meeting to build cooperation for health between nations heralded the governance of international health concerning the scale of the nation-state and the organization of the interrelations between them.
Alain Vaguet
doaj   +1 more source

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