Results 61 to 70 of about 91,439 (301)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Statistic Analysis of Bank Deposit Insurance System in the Russian Federation

open access: yesВестник Российского экономического университета имени Г. В. Плеханова
In the last decade in crisis conditions of country economy, withdrawal of licenses of many commercial banks due to deterioration of their finance standing and low confidence of people to the banking system because of insufficient finance literacy the ...
E. V. Lapteva
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

LICENCIAS OBLIGATORIAS POR RAZONES DE SALUD PÚBLICA EN CHILE: UN ANÁLISIS COMPARATIVO CON EL ACUERDO SOBRE LOS ADPIC Compulsory licenses for reasons of public health in Chile: a comparative analysis with the trips agreement

open access: yesIus et Praxis, 2010
En la implementación de sus múltiples acuerdos internacionales en materia de propiedad intelectual, Chile ha modificado su Ley de Propiedad Industrial, la cual reglamenta el sistema de patentes, reconociendo la patentabilidad de productos farmacéuticos ...
Alberto Cerda Silva
doaj  

Science-based health innovation in Uganda: creative strategies for applying research to development

open access: yesBMC International Health and Human Rights, 2010
Background Uganda has a long history of health research, but still faces critical health problems. It has made a number of recent moves towards building science and technology capacity which could have an impact on local health, if innovation can be ...
Daar Abdallah S   +4 more
doaj   +1 more source

The Case for CAPSL: Architectural Solutions to Licensing and Distribution in Emerging Music Markets [PDF]

open access: yes, 2015
Compulsory licensing in music has paved the way for a limited class of new noninteractive services. However, innovation and competition are stifled in the field of interactive or otherwise novel services due to high transaction costs inherent in direct ...
Duncan, Cody
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Mandatory vaccinations in European countries, undocumented information, false news and the impact on vaccination uptake: the position of the Italian pediatric society. [PDF]

open access: yes, 2018
BACKGROUND: High rates of vaccination coverage are important in preventing infectious diseases. Enforcing mandatory vaccinations is one of the strategies that some Countries adopted to protect the community when vaccination coverage is not satisfactory ...
Bozzola E   +5 more
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Brief of Law Professors as Amicus Curiae in Support of Respondent [PDF]

open access: yes, 2003
Inventors lacking assurance of a market, or even the right to practice patented inventions, face considerable risk. Those who qualify for patents, in return for disclosure, receive only the assistance of the courts in excluding others from economic ...
Field, Thomas G., Jr   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy