Results 61 to 70 of about 27,920 (229)

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Against Hayek [PDF]

open access: yes
Presents a critical analysis of Hayek in the light of modern computability and economic computability theory.Hayek, Computability ...
Cockshott, W. Paul, Cottrell, Allin
core   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Quantum randomness and value indefiniteness

open access: yes, 2008
As computability implies value definiteness, certain sequences of quantum outcomes cannot be computable.Comment: 13 pages ...
Calude, Cristian S., Svozil, Karl
core   +3 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Amenability and computability

open access: yes, 2020
In this paper we extend the approach of M. Cavaleri to effective amenability to the class of computably enumerable groups, i.e. in particular we do not assume that groups are finitely generated.
Duda, Karol
core  

Computing with Functionals—Computability Theory or Computer Science?

open access: yesBulletin of Symbolic Logic, 2006
AbstractWe review some of the history of the computability theory of functionals of higher types, and we will demonstrate how contributions from logic and theoretical computer science have shaped this still active subject.
openaire   +3 more sources

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