Results 61 to 70 of about 3,053,426 (341)
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Computing-Model and Computing-Hardware Selection for ICT Under Societal and Judicial Constraints
IEEE AccessThis article discusses a formalization of aspects of Cyber-Sovereignty (CyS) for information and communication technology (ICT), linking them to technological trustworthiness and deriving an associated paradigm for hard- and software design. The upcoming
Yannik N. Bock +3 more
doaj +1 more source
Electronic Proceedings in Theoretical Computer Science, 2010 Computation with advice is suggested as generalization of both computation with discrete advice and Type-2 Nondeterminism. Several embodiments of the generic concept are discussed, and the close connection to Weihrauch reducibility is pointed out.
Vasco Brattka, Arno Pauly
doaj +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
LOGIC, PRIMES AND COMPUTATION: A TALE OF UNREST
TASK Quarterly, 2005 The early connections between Mathematical Logic and Computer Science date back to the thirties and to the birth itself of modern Theoretical Computer Science, and concern computability.
STEFANO LEONESI, CARLO TOFFALORI
doaj
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Diagonal Anti-Mechanist Arguments
Studia Semiotyczne, 2020 DOI: http://doi.org/10.26333/sts.xxxiv1.09 Gödel’s first incompleteness theorem is sometimes said to refute mechanism about the mind. §1 contains a discussion of mechanism.
David Kashtan
doaj
Studies in Logic, Grammar and Rhetoric, 2016 The aim of this paper is an attempt to give an answer to the question what does it mean that a computational system is intelligent. We base on some theses that though debatable are commonly accepted.
Trzęsicki Kazimierz
doaj +1 more source
The geometric approach to quantum correlations: computability versus reliability [PDF]
, 2013 We propose a modified metric based on the Hilbert–Schmidt norm and adopt it to define a rescaled version of the geometric measure of quantum discord. Such a measure is found not to suffer from pathological dependence on state purity.
T. Tufarelli +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source