Results 61 to 70 of about 29,886 (270)

Computability and analysis: the legacy of Alan Turing

open access: yes, 2009
We discuss the legacy of Alan Turing and his impact on computability and analysis.Comment: 49 ...
Avigad, Jeremy, Brattka, Vasco
core   +2 more sources

Weihrauch-completeness for layerwise computability [PDF]

open access: yesLogical Methods in Computer Science, 2018
We introduce the notion of being Weihrauch-complete for layerwise computability and provide several natural examples related to complex oscillations, the law of the iterated logarithm and Birkhoff's theorem. We also consider hitting time operators, which
Arno Pauly, Willem Fouché, George Davie
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Closed Sets and Operators thereon: Representations, Computability and Complexity [PDF]

open access: yesLogical Methods in Computer Science, 2018
The TTE approach to Computable Analysis is the study of so-called representations (encodings for continuous objects such as reals, functions, and sets) with respect to the notions of computability they induce.
Carsten Rösnick-Neugebauer
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The Task-Based Approach: A New Paradigm for Building Trustworthy Artificial Intelligence

open access: yesИзвестия Иркутского государственного университета: Серия "Математика"
While AI systems excel at reasoning within formal frameworks, their tendency to hallucinate remains a critical challenge. This paper proposes a task-based approach to enhance reliability.
A.V. Nechesov   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Intuitionistic computability logic [PDF]

open access: yes, 2006
Computability logic (CL) is a systematic formal theory of computational tasks and resources, which, in a sense, can be seen as a semantics-based alternative to (the syntactically introduced) linear logic.
Japaridze, Giorgi
core   +2 more sources

Can Ai Be Intelligent?

open access: yesStudies in Logic, Grammar and Rhetoric, 2016
The aim of this paper is an attempt to give an answer to the question what does it mean that a computational system is intelligent. We base on some theses that though debatable are commonly accepted.
Trzęsicki Kazimierz
doaj   +1 more source

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