Results 71 to 80 of about 30,213 (286)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
A Complete Theory of Everything (Will Be Subjective)
Algorithms, 2010 Increasingly encompassing models have been suggested for our world. Theories range from generally accepted to increasingly speculative to apparently bogus.
Marcus Hutter
doaj +1 more source
COMPUTER SIMULATION AND COMPUTABILITY OF BIOLOGICAL SYSTEMS [PDF]
, 1986 The ability to simulate a biological organism by employing a computer is related to the ability of the computer to calculate the behavior of such a dynamical system, or the "computability" of the system.* However, the two questions of computability and ...
Baianu, Professor I.C., Lin, Ms. H.C.
core
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
HİLBERT’İN BİÇİMSELLEŞTİRME PROGRAMININ FELSEFESİ
Felsefe Dünyası, 2014 Bu yazıda, Hilbert’in biçimselleştirme programına kadar giden matematikfelsefesindeki önemli krizlerden bahsedilmiştir. Hilbert’in programınıngerçekleşemeyeceğini gösteren Gödel’in eksiklik teoremi gibi programınsonuçları ve nedenleri tartışılmıştır ...
Ahmet Çevik
doaj
Presents a critical analysis of Hayek in the light of modern computability and economic computability theory.Hayek, Computability ...
Cockshott, W. Paul, Cottrell, Allin
core +1 more source
Designing computer circuits with a computer
Proceedings of the 1956 11th ACM national meeting on - ACM '56, 1956 The circuit to be considered is that of a transistor flipflop as shown in Figure 1. All polarities are chosen for NPN transistors. In this analysis, the transistor re, rb, and rc, will be assumed neglibible for simplicity. It will also be assumed that (equation) where α is the current gain of the transistor.
openaire +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
-Generic Computability, Turing Reducibility and Asymptotic Density
, 2010 Generic computability has been studied in group theory and we now study it in the context of classical computability theory. A set A of natural numbers is generically computable if there is a partial computable function f whose domain has density 1 and ...
Carl G. Jockusch, Jr., Paul E. Schupp
core +3 more sources