Results 81 to 90 of about 8,869 (303)

Is Every Cognitive Phenomenon Computable?

open access: yesMathematics
According to the Church–Turing thesis, the limit of what is computable is bounded by Turing machines. Following from this, given that general computable functions formally describe the notion of recursive mechanisms, it is sometimes argued that every ...
Fernando Rodriguez-Vergara   +1 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Computability and Complexity in Analysis

open access: yes, 2008
Computability and Complexity in ...
Schröder,Matthias   +7 more
core   +1 more source

A Complete Theory of Everything (Will Be Subjective)

open access: yesAlgorithms, 2010
Increasingly encompassing models have been suggested for our world. Theories range from generally accepted to increasingly speculative to apparently bogus.
Marcus Hutter
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Asymptotic Notions of Computability [PDF]

open access: yes
In computability theory, the classical definition of a Turing machine M solving a problem requires M to always halt and always give the right answer. If we relax the “always” to “almost always”, we give rise to asymptotic notions of computability, where ...
Royer, Tiago
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Research on the promotion of clinical practice guidelines implementation (Ⅸ): a framework design for computable formalization of diagnostic and therapeutic process knowledge and construction of knowledge praphs in clinical practice guidelines [PDF]

open access: yesYixue xinzhi zazhi
Clinical practice guidelines contain substantial diagnostic and therapeutic process knowledge to guide clinical decisions. However, since this knowledge is often expressed in natural language, it is difficult for computers to directly understand and ...
RUAN Siyuan   +8 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Computability and Complexity in Analysis

open access: yes, 2010
Computability and Complexity in ...
Ko, Ker-I   +5 more
core   +1 more source

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