Results 81 to 90 of about 30,213 (286)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Is Every Cognitive Phenomenon Computable?

open access: yesMathematics
According to the Church–Turing thesis, the limit of what is computable is bounded by Turing machines. Following from this, given that general computable functions formally describe the notion of recursive mechanisms, it is sometimes argued that every ...
Fernando Rodriguez-Vergara   +1 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Physical computing: a category theoretic perspective on physical computation and system compositionality

open access: yesJournal of Physics: Complexity
This paper introduces a category theory-based framework to redefine physical computing in light of advancements in quantum computing and non-standard computing systems.
Nima Dehghani, Gianluca Caterina
doaj   +1 more source

Intuitionistic computability logic [PDF]

open access: yes, 2006
Computability logic (CL) is a systematic formal theory of computational tasks and resources, which, in a sense, can be seen as a semantics-based alternative to (the syntactically introduced) linear logic.
Japaridze, Giorgi
core   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Computability and Non-computability Issues in Amorphous Computing [PDF]

open access: yes, 2012
Amorphous computing systems consist of a huge set of tiny simple stationary or mobile processors whose computational, communication and sensory part is reduced to an absolute minimum. In an airborne medium the processors communicate via a short-range radio while in a waterborne medium via molecular communication. In some cases the computational part of
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

LOGIC, PRIMES AND COMPUTATION: A TALE OF UNREST

open access: yesTASK Quarterly, 2005
The early connections between Mathematical Logic and Computer Science date back to the thirties and to the birth itself of modern Theoretical Computer Science, and concern computability.
STEFANO LEONESI, CARLO TOFFALORI
doaj  

Home - About - Disclaimer - Privacy