Results 91 to 100 of about 30,213 (286)

To compute or not to compute?

open access: yesJournal of Traffic and Transportation Engineering (English Edition), 2019
In a previous paper “to retrofit or not to retrofit?” (Nuti and Vanzi, 2003) a straightforward procedure able to forecast the economic return of seismic structural upgrading was presented. More recently, the authors realized that the final mathematical results can be much simplified so as to allow back-of-an-envelope computation.
Fiore A.   +5 more
openaire   +6 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Weighted Least Squares Regression with the Best Robustness and High Computability

open access: yesAxioms
A novel regression method is introduced and studied. The procedure weights squared residuals based on their magnitude. Unlike the classic least squares which treats every squared residual as equally important, the new procedure exponentially down-weights
Yijun Zuo, Hanwen Zuo
doaj   +1 more source

Basics of Intensionalized Data: Presets, Sets, and Nominats [PDF]

open access: yesComputer Science Journal of Moldova, 2012
In the paper we consider intensional aspects of the notion of data. We advocate an idea that traditional set-theoretic platform should be enhanced with new data structures having explicit intensional component.
Mykola Nikitchenko, Alexey Chentsov
doaj  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Features and transaction modes of data products in data markets

open access: yes大数据, 2022
Developing the markets of data as a factor of production is the key in the efficient allocation of data factor.However, the early practices of data markets in China have revealed a series of problems, which urgently calls for a systematic review and ...
Lihua HUANG   +4 more
doaj  

Amenability and computability

open access: yes, 2020
In this paper we extend the approach of M. Cavaleri to effective amenability to the class of computably enumerable groups, i.e. in particular we do not assume that groups are finitely generated.
Duda, Karol
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

On computable subgroups of the group of all unitriangular matrices over a ring

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы, 2017
The problems of existence and uniqueness of computable numberings are fundamental in theory of computably numbered groups. In connection with the development of the theory of algorithms a study of the problems of computability of important classes of ...
R.K. Tyulyubergenev
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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