HybSuite: An integrated pipeline for hybrid capture phylogenomics from reads to trees
Abstract Premise Hybrid capture sequencing (Hyb‐Seq) is a widely used approach in phylogenomics, providing efficient access to targeted genomic regions. However, deriving high‐quality phylogenetic trees from raw sequencing reads requires extensive bioinformatics processing, which increases complexity, the risk of errors, and challenges in file ...
Yu‐Xuan Liu +8 more
wiley +1 more source
Computational design of class II MHC binding peptide with sequence-based evolution information. [PDF]
Cao Y, Li Y, Ren W, Li W, Yan Z.
europepmc +1 more source
Abstract Premise The recovery of non‐target organism reads, especially when whole organisms are sampled, constitutes a great opportunity for studying microbial communities. The increase in whole genome sequencing feasibility and the development of new marker‐based pipelines enable the use of short reads to study bacterial communities associated with ...
Ixchel S. González‐Ramírez +3 more
wiley +1 more source
Training biologists in Unix command-line skills: From curriculum to interactive online tutorials. [PDF]
Khamvongsa-Charbonnier L +8 more
europepmc +1 more source
BINSEQ: A family of high-performance binary formats for nucleotide sequences. [PDF]
Teyssier N, Dobin A.
europepmc +1 more source
Chicken Pulmonary MicroRNAs Targeting the PB2 (Segment 1) of Avian Influenza Virus
The PB2 segment of H5N1 is essential for replication and host adaptation. We screened 200 miRNAs and identified five (gga‐miR‐17‐3p, gga‐miR‐29a‐5p, gga‐miR‐1718, gga‐miR‐16c‐5p, and gga‐miR‐1744‐5p) using thermodynamic stability of heteroduplex, seed sequence complementarity, conservation, and accessibility, offering insights into host antiviral ...
Akanksha Choudhary +7 more
wiley +1 more source
Diagnosing scientific replicability through probabilistic distinguishability. [PDF]
Wang P, Cao H, Wen X.
europepmc +1 more source
The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang +10 more
wiley +1 more source
Challenges and Advances in Bioinformatics and Computational Biology. [PDF]
Si T, Gong H.
europepmc +1 more source
Precision medicine in paediatrics: Progress and priorities
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain +3 more
wiley +1 more source

