Results 81 to 90 of about 1,973,231 (200)

RBLOSUM performs better than CorBLOSUM with lesser error per query

open access: yesBMC Research Notes, 2018
Objective BLOSUM matrices serve as standard matrices for many protein sequence alignment programs. BLOSUM matrices have been constructed using BLOCKS version5.0 with 27,102 BLOCKS, whereas the latest updated version14.3 has 6,739,916 BLOCKS. We read with
Renganayaki Govindarajan   +2 more
doaj   +1 more source

Agents in bioinformatics, computational and systems biology [PDF]

open access: yes, 2007
The adoption of agent technologies and multi-agent systems constitutes an emerging area in bioinformatics. In this article, we report on the activity of the Working Group on Agents in Bioinformatics (BIOAGENTS) founded during the first AgentLink III ...
Cannata, Nicola   +36 more
core   +1 more source

Structural Bioinformatics and Big Data Analytics: A mini-review [PDF]

open access: yes, 2017
Structural Biology and Structural Bioinformatics are two complementary areas that deal with three dimensional structures of biomolecules. With the advent of high-throughput techniques and automation of identifying structures there is a barrage of data ...
Yennamalli, Ragothaman M; Jaypee University of Information Technology
core  

The Third Annual Meeting of the European Virus Bioinformatics Center [PDF]

open access: yes, 2019
The Third Annual Meeting of the European Virus Bioinformatics Center (EVBC) took place in Glasgow, United Kingdom, 28–29 March 2019. Virus bioinformatics has become central to virology research, and advances in bioinformatics have led to improved ...
Lycett, Samantha; id_orcid   +108 more
core   +4 more sources

PACKMAN-Molecule: Python toolbox for structural bioinformatics [PDF]

open access: yes, 2022
PACKMAN-molecule is a Structural Bioinformatics toolbox in the form of an Application Programming Interface that contains several utilities that can be used for structural bioinformatics applications. It has already been used in several applications, and
Jernigan, Robert, Khade, Pranav
core  

Integrated cancer cell-specific single-cell RNA-seq datasets of immune checkpoint blockade-treated patients

open access: yesScientific Data
Immune checkpoint blockade (ICB) therapies have emerged as a promising avenue for the treatment of various cancers. Despite their success, the efficacy of these treatments is variable across patients and cancer types. Numerous single-cell RNA-sequencing (
Mahnoor N. Gondal   +2 more
doaj   +1 more source

Computational Intelligence in Bioinformatics

open access: yesJournal of Proteomics & Bioinformatics, 2014
Since the term ‘bioinformatics’ was coined in 1970 [1], the field of bioinformatics has become relatively mature allowing high-throughput whole genome sequencing and making computer-aided drug design an essential part of drug discovery. With the needs of addressing ever more complex problems in a faster and more accurate manner, the bioinformatics ...
openaire   +1 more source

Computational drug repositioning approach to predict multi-target therapeutics for epilepsy

open access: yesScientific Reports
Epilepsy affects millions of people globally, with approximately one-third of patients experiencing drug-resistant seizures. Developing new anti-epileptic drugs is time-intensive and costly, prompting interest in computational drug repositioning ...
Pawan Kumar   +4 more
doaj   +1 more source

Computational Pipelines and Workflows in Bioinformatics

open access: yes, 2019
The recent growth in volume and complexity of biological data has simultaneously pushed the development of computational pipelines used in corresponding analyses.
Shigemizu, Daichi   +5 more
core   +1 more source

Bioinformatics pre-selection of thioredoxin/glutaredoxin target proteins for the construction of cellular redox regulatory network [PDF]

open access: yes, 2012
Lee H-M. Bioinformatics pre-selection of thioredoxin/glutaredoxin target proteins for the construction of cellular redox regulatory network. Bielefeld: Bielefeld University; 2012.The gradually accumulated knowledge of molecular interaction is assembled ...
Lee, Hang-Mao
core  

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