Results 151 to 160 of about 4,681,443 (397)
Molecular Visualization of Computational Biology Data: A Survey of Surveys
Eurographics Conference on Visualization, 2017 Visualizations for computational biology have been developing for over 50 years. With recent advances in both computational biology and computer graphics techniques, these fields have witnessed rapid technological advances in the last decade. Thus, coping
Naif Alharbi +7 more
semanticscholar +1 more source
Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations
FEBS Open Bio, EarlyView.We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo +2 more
wiley +1 more source
Biology-Derived Algorithms in Engineering Optimization [PDF]
Yang X.-S., Biology-derived algorithms in engineering optimization
(chapter 32), in: Handbook of Bioinspired Algorithms and Applications (Eds.
S. Olarius and A. Y. Zomaya), Chapman & Hall/CRC Press, pp. 589-600 (2005), 2010 Biology-derived algorithms are an important part of computational sciences, which are essential to many scientific disciplines and engineering applications. Many computational methods are derived from or based on the analogy to natural evolution and biological activities, and these biologically inspired computations include genetic algorithms, neural ...
arxiv
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
Athena: Modular CAM/CAD Software for Synthetic Biology [PDF]
arXiv, 2009 Synthetic biology is the engineering of cellular networks. It combines principles of engineering and the knowledge of biological networks to program the behavior of cells. Computational modeling techniques in conjunction with molecular biology techniques have been successful in constructing biological devices such as switches, oscillators, and gates ...
arxiv
Where next for the reproducibility agenda in computational biology?
BMC Systems Biology, 2016 BackgroundThe concept of reproducibility is a foundation of the scientific method. With the arrival of fast and powerful computers over the last few decades, there has been an explosion of results based on complex computational analyses and simulations ...
Joanna Lewis +4 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
Parameter inference and model selection in signaling pathway models [PDF]
arXiv, 2009 To support and guide an extensive experimental research into systems biology of signaling pathways, increasingly more mechanistic models are being developed with hopes of gaining further insight into biological processes. In order to analyse these models, computational and statistical techniques are needed to estimate the unknown kinetic parameters ...
arxiv
Correction: Plasticity-Driven Self-Organization under Topological Constraints Accounts for Non-random Features of Cortical Synaptic Wiring. [PDF]
PLoS Computational Biology, 2016 PLOS Computational Biology Staff
doaj +1 more source
FEBS Open Bio, EarlyView.The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli +15 more
wiley +1 more source