Results 131 to 140 of about 3,347,103 (312)

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Development of a New Pipeline for Identification and Characterization of Micro RNAs from Plants [PDF]

open access: yes, 2016
Open source microRNA analysis pipelines for next generation sequencing data (NGS) often make necessary use and working knowledge of command line interface, massive data processing resources and expertise which is a daunting task for biologists.
Jinu, Thomas; Jawaharlal Nehru Tropical Botanic Garden & Research Institute (JNTBGRI)   +1 more
core  

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Computing Biology

open access: yesPLOS Computational Biology, 2016
Ruth Nussinov, Jason A. Papin
openaire   +5 more sources

Foundations of Computational and Systems Biology

open access: yes, 2004
Serving as an introduction to computational biology, this course emphasizes the fundamentals of nucleic acid and protein sequence analysis, structural analysis, and the analysis of complex biological systems.
Keating, Amy   +3 more
core  

Computational Probability for Systems Biology

open access: yes
Stochastic models of biological networks properly take the randomness of molecular dynamics in living cells into account. Numerical solution approaches inspired by computational methods from applied probability can efficiently yield accurate results and ...
Werner Sandmann, Verena Wolf.
core   +1 more source

DEN: an R-Bioconductor based package to extract active sub-networks from human interaction map by integrating gene-expression data [PDF]

open access: yes, 2015
Living cells are complex, dynamic, self-regulatory, interactive systems, showing differential states across time and space. Complexity of cellular systems is highlighted with the multi-layered regulatory mechanisms involving the interactions between bio ...
Desai, Sanket Shashikant; School of Biotechnology, IGNOU- International Institute of Information Technology, Center of Excellence for Advanced Research and Education, P-14, Rajiv Gandhi Infotech Park, Phase-1, Hinjewadi, Pune (www.isquareit.ac.in)
core   +2 more sources

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