Results 101 to 110 of about 1,437,104 (331)

The computational complexity of convex bodies

open access: yes, 2006
We discuss how well a given convex body B in a real d-dimensional vector space V can be approximated by a set X for which the membership question: ``given an x in V, does x belong to X?'' can be answered efficiently (in time polynomial in d).
Barvinok, Alexander, Veomett, Ellen
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Quantum sampling algorithms, phase transitions, and computational complexity [PDF]

open access: hybrid, 2021
Dominik S. Wild   +4 more
openalex   +1 more source

Applying computational complexity to the emergence of classicality [PDF]

open access: yes, 2013
Can the computational complexity theory of computer science and mathematics say something new about unresolved problems in quantum physics? Particularly, can the P versus NP question in the computational complexity theory be a factor in the elucidation ...
Bolotin, Arkady
core  

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

Computational complexity, algorithmic scope, and evolution

open access: yesJournal of Physics: Complexity
Biological systems are widely regarded as performing computations. It is much less clear, however, what exactly is computed and how biological computation fits within the framework of standard computer science.
Leonhard Sidl   +7 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Bosons vs. Fermions – A computational complexity perspective [PDF]

open access: yesRevista Brasileira de Ensino de Física
Recent years have seen a flurry of activity in the fields of quantum computing and quantum complexity theory, which aim to understand the computational capabilities of quantum systems by applying the toolbox of computational complexity theory. This paper
Daniel Jost Brod
doaj   +2 more sources

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