Results 71 to 80 of about 3,355,376 (309)
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
08381 Abstracts Collection – Computational Complexity of Discrete Problems [PDF]
, 2008 From the 14th of September to the 19th of September, the Dagstuhl Seminar 08381 ``Computational Complexity of Discrete Problems'' was held in Schloss Dagstuhl - Leibniz Center for Informatics.
van Melkebeek, Dieter +3 more
core +1 more source
What makes a “regime complex” complex? It depends
, 2021 What makes the collections of international institutions or regimes governing various domains—called in theliterature regime, institutional, or governance complexes—“complex”?
Hollway, James
core +1 more source
Optical Computing and Computational Complexity
, 2006 This work concerns the computational complexity of a model of computation that is inspired by optical computers. The model is called the continuous space machine and operates in discrete timesteps over a number of two-dimensional images of fixed size and arbitrary spatial resolution.
openaire +2 more sources
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
The role of twins in computing planar supports of hypergraphs
Journal of Graph Algorithms and ApplicationsA support or realization of a hypergraph $\mathcal{H}$ is a graph \(G\) on the same vertex set as \(\mathcal{H}\) such that for each hyperedge of $\mathcal{H}$ it holds that its vertices induce a connected subgraph of $G$.
René van Bevern +4 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
04421 Abstracts Collection – Algebraic Methods in Computational Complexity [PDF]
, 2005 From 10.10.04 to 15.10.04, the Dagstuhl Seminar 04421 ``Algebraic Methods in Computational Complexity'' was held in the International Conference and Research Center (IBFI), Schloss Dagstuhl.
Buhrman, Harry +2 more
core +1 more source
Comorbidity patterns in cardiovascular diseases: the role of life-stage and socioeconomic status
Frontiers in Cardiovascular MedicineCardiovascular diseases stand as a prominent global cause of mortality, their intricate origins often entwined with comorbidities and multimorbid conditions.
Héctor A. Cruz-Ávila +5 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source