Results 41 to 50 of about 410,375 (269)
Heuristics for Quantum Computing Dealing with 3-SAT
The SAT problem is maybe one of the most famous NP-complete problems. This paper deals with the 3-SAT problem. We follow a sort of incremental strategy to save computational costs with respect to the classical quantum computing approach.
Jose J. Paulet +5 more
doaj +1 more source
Vertical equilibrium simulation for industrial-scale CO2 storage in heterogeneous aquifers
Vertical equilibrium (VE) simulation has re-emerged recently as an efficient approach for simulating geological CO2 storage in aquifers. The approach is well-established and traditionally applied for simulating storage in homogeneous formations.
Hatem Alamara +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Efficiency of universal parallel computers [PDF]
We consider parallel computers (PC's) with fixed communication network and bounded degree. We deal with the following question: How efficiently can one PC, a so-called universal PC, simulate each PC with n processors? This question is asked in [1] where a universal PC with O(n) processors and time loss O(log(n)) is constructed.
openaire +5 more sources
Extended Target GMPHD Filter Based on Mean Shift and Graph Structure [PDF]
In view of excessive measurements partition number, a large computation load of extended target tracking and leakage estimation when the extended targets cross, an extended target tracking algorithm based on GMPHD with mean shift and graph structure is ...
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
In the current scenario, where environmental concern determines the evolution of passenger cars, hybrid electric vehicles (HEV) represent a hub in the automotive sector to reach net-zero CO2 emissions.
Vincenzo De Bellis +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
A High Efficient Fluid-Structure Interaction Method for Flutter Analysis of Mistuned [PDF]
The time cost is very high by direct fluid-structure interaction method for mistuned bladed disk structures, so aerodynamic loads generally are ignored or treated as small perturbations in traditional flutter analysis.
doaj +1 more source

