Results 71 to 80 of about 1,711,553 (293)

Editorial: Quantum computing applications in computational engineering

Frontiers in Mechanical Engineering, 2023
René Steijl, Romit Maulik
doaj   +1 more source

Engineering Design under Imprecise Probabilities: Computational Complexity

Cubo, 2011
In engineering design problems, we want to make sure that a certain quantity c of the designed system lies within given bounds - or at least that the probability of this quantity to be outside these bounds does not exceed a given threshold.
Vladik Kreinovich
doaj  

Topology optimization aided structural design: Interpretation, computational aspects and 3D printing

Heliyon, 2017
Construction industry has a major impact on the environment that we spend most of our life. Therefore, it is important that the outcome of architectural intuition performs well and complies with the design requirements.
Georgios Kazakis, Ioannis Kanellopoulos, Stefanos Sotiropoulos, Nikos D. Lagaros   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Finite element analysis of double-diffusive natural convection in a porous triangular enclosure filled with Al2O3-water nanofluid in presence of heat generation

Heliyon, 2016
The problem of double-diffusive natural convection of Al2O3-water nanofluid in a porous triangular enclosure in presence of heat generation has been studied numerically in this paper.
Raju Chowdhury, Salma Parvin, Md. Abdul Hakim Khan   +2 more
doaj   +1 more source

A Cyberinfrastructure for BigData Transportation Engineering [PDF]

, 2018
Big Data-driven transportation engineering has the potential to improve utilization of road infrastructure, decrease traffic fatalities, improve fuel consumption, decrease construction worker injuries, among others.
Islam, Md Johirul, Rajan, Hridesh, Rajan, Hridesh, Sharma, Anuj, Sharma, Anuj   +4 more
core   +3 more sources

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Systematic Applications of Metabolomics in Metabolic Engineering

Metabolites, 2012
The goals of metabolic engineering are well-served by the biological information provided by metabolomics: information on how the cell is currently using its biochemical resources is perhaps one of the best ways to inform strategies to engineer a cell to
Robert A. Dromms, Mark P. Styczynski
doaj   +1 more source