Results 71 to 80 of about 5,454,633 (299)

Editorial: Quantum computing applications in computational engineering

open access: yesFrontiers in Mechanical Engineering, 2023
René Steijl, Romit Maulik
doaj   +1 more source

Engineering Design under Imprecise Probabilities: Computational Complexity

open access: yesCubo, 2011
In engineering design problems, we want to make sure that a certain quantity c of the designed system lies within given bounds - or at least that the probability of this quantity to be outside these bounds does not exceed a given threshold.
Vladik Kreinovich
doaj  

Computational Fluid Dynamics Methods and Their Applications in Medical Science

open access: yesStudies in Logic, Grammar and Rhetoric, 2016
As defined by the National Institutes of Health: “Biomedical engineering integrates physical, chemical, mathematical, and computational sciences and engineering principles to study biology, medicine, behavior, and health”.
Kowalewski Wojciech   +4 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Topology optimization aided structural design: Interpretation, computational aspects and 3D printing

open access: yesHeliyon, 2017
Construction industry has a major impact on the environment that we spend most of our life. Therefore, it is important that the outcome of architectural intuition performs well and complies with the design requirements.
Georgios Kazakis   +3 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Computational engineering analysis with the new-generation space–time methods

open access: yesComputational Mechanics, 2014
This is an overview of the new directions we have taken the space–time (ST) methods in bringing solution and analysis to different classes of computationally challenging engineering problems.
K. Takizawa
semanticscholar   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Finite element analysis of double-diffusive natural convection in a porous triangular enclosure filled with Al2O3-water nanofluid in presence of heat generation

open access: yesHeliyon, 2016
The problem of double-diffusive natural convection of Al2O3-water nanofluid in a porous triangular enclosure in presence of heat generation has been studied numerically in this paper.
Raju Chowdhury   +2 more
doaj   +1 more source

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