Results 61 to 70 of about 6,395,720 (300)

IMPACT OF COMPUTATIONAL RADIATION TRANSFER ON SCIENCE, ENGINEERING AND SOCIETY

, 2017
In this presentation, we will present a journey on the development of physics of radiation transfer and the related computational methodologies. We will highlight many applications of radiation transfer on fundamental sciences and engineering disciplines.
M. Pinar Menguc, Mengüç, Mustafa Pınar   +1 more
core   +1 more source

Editorial: Quantum computing applications in computational engineering

Frontiers in Mechanical Engineering, 2023
René Steijl, Romit Maulik
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Computational Methods in Structural Engineering: Current Advances and Future Perspectives

This brief editorial introduces the Special Issue “Computational Methods in Structural Engineering”. This Special Issue brings together recent advances in computational approaches—including finite element modeling, machine learning ...
Vagelis Plevris, Mahdi Kioumarsi, Manolis Georgioudakis   +2 more
core   +1 more source

Engineering Design under Imprecise Probabilities: Computational Complexity

Cubo, 2011
In engineering design problems, we want to make sure that a certain quantity c of the designed system lies within given bounds - or at least that the probability of this quantity to be outside these bounds does not exceed a given threshold.
Vladik Kreinovich
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Computational Methods in Wind Engineering

In wind engineering, in parallel to all other engineering disciplines, the impact of computational methods is rapidly increasing. As far as computational aspects are concerned, wind engineering embodies a series of specific challenges, including the ...

core   +1 more source

Computational Fluid Dynamics Methods and Their Applications in Medical Science

Studies in Logic, Grammar and Rhetoric, 2016
As defined by the National Institutes of Health: “Biomedical engineering integrates physical, chemical, mathematical, and computational sciences and engineering principles to study biology, medicine, behavior, and health”.
Kowalewski Wojciech, Roszak Magdalena, Kołodziejczak Barbara, Ren-Kurc Anna, Bręborowicz Andrzej   +4 more
doaj   +1 more source

Topology optimization aided structural design: Interpretation, computational aspects and 3D printing

Heliyon, 2017
Construction industry has a major impact on the environment that we spend most of our life. Therefore, it is important that the outcome of architectural intuition performs well and complies with the design requirements.
Georgios Kazakis, Ioannis Kanellopoulos, Stefanos Sotiropoulos, Nikos D. Lagaros   +3 more
doaj   +1 more source