Results 51 to 60 of about 1,711,553 (293)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Introducing ‘Neuromorphic Computing and Engineering’
Neuromorphic Computing and Engineering, 2021 Abstract The standard nature of computing is currently being challenged by a range of problems that start to hinder technological progress. One of the strategies being proposed to address some of these problems is to develop novel brain-inspired processing methods and technologies, and apply them to a wide range of application ...
openaire +2 more sources
Analytical Methods in Wave Scattering and Diffraction Volume I
Mathematics, 2023 Boundary value problems (BVPs) pertaining to scattering and radiation by devices that support novel wave phenomena are of primary importance in applied and computational mathematics, computational physics and engineering [...]
Nikolaos L. Tsitsas
doaj +1 more source
Computer graphics data conditioning [PDF]
, 1968 Graphics data conditioning program expedites engineering analysis of flight data and ensures timely correction of measurement errors. By adding interactive computer graphic displays to existing data conditioning programs, computational results are ...
Hagenau, K. H., Mc Millen, G. C.
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Integrated Computational Materials Engineering of Fire-Resistant Steels
Materials & DesignWe explore a wide compositional space of low-carbon steel, containing 11 alloying elements, assess its feasibility for fire-resistant applications via modeling yield strength at elevated temperatures.
Alireza Zargaran +9 more
doaj +1 more source
Computational Study of Protein-Ligand Unbinding for Enzyme Engineering
Frontiers in Chemistry, 2019 The computational prediction of unbinding rate constants is presently an emerging topic in drug design. However, the importance of predicting kinetic rates is not restricted to pharmaceutical applications.
Sérgio M. Marques +5 more
doaj +1 more source
On the parabolic equation method in internal wave propagation [PDF]
, 2006 A parabolic equation for the propagation of periodic internal waves over varying bottom topography is derived using the multiple-scale perturbation method. Some computational aspects of the numerical implementation are discussed. The results of numerical
A.D. Zakharenko +22 more
core +2 more sources
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source