Results 41 to 50 of about 155,395 (263)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Current Open Problems in Discrete and Computational Geometry

open access: yesМоделирование и анализ информационных систем, 2012
We have selected problems that may not yet be well known, but have the potential to push the research in interesting directions. In particular, we state problems that do not require specific knowledge outside the standard circle of ideas in discrete ...
H. Edelsbrunner, A. Ivanov, R. Karasev
doaj   +3 more sources

Local and Global Approaches to Fracture Mechanics Using Isogeometric Analysis Method

open access: yesJournal of Applied and Computational Mechanics, 2015
In the present research, implementations of different computational geometry technologies in isogeometric analysis framework for computational fracture mechanics are investigated.
Abdolghafoor Khademalrasoul, Reza Naderi
doaj   +1 more source

Distributed control of mobile robots in an environment with static obstacles

open access: yesIET Cyber-systems and Robotics, 2021
This study addresses the problem of deploying a group of mobile robots over a non‐convex region with obstacles. Assuming that the robots are equipped with omnidirectional range sensors of common radius, disjoint subsets of the sensed area are assigned to
Konstantinos Giannousakis, Anthony Tzes
doaj   +1 more source

An Automatic Process for the Application of Building Permits

open access: yesBuildings, 2022
Building Information Modeling is an essential element for the digitization of the construction industry and forms the basis for the exchange of model-based data. In order to exploit the full potential of digitization, it is necessary for all stakeholders
Kurt Battisti   +7 more
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

On the Intersection of Computational Geometry Algorithms with Mobile Robot Path Planning

open access: yesAlgorithms, 2023
In the mathematical discipline of computational geometry (CG), practical algorithms for resolving geometric input and output issues are designed, analyzed, and put into practice.
Ehsan Latif, Ramviyas Parasuraman
doaj   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

The importance of computational geometry for digital cartography

open access: yesGeoinformatics FCE CTU, 2009
This paper describes the use of computational geometry concepts in the digital cartography.  It presents an importance of 2D geometric structures, geometric operations and procedures for automated or semi automated simplification process. This article is
Tomáš Bayer
doaj   +1 more source

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