Results 51 to 60 of about 206,500 (313)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Coverage improvement using Voronoi diagrams in directional sensor networks
IET Wireless Sensor Systems, 2021 Recently, the area coverage problem has emerged in the directional sensor network (DSN), where the sensor's sensed area depends on its working direction and viewing angle.
Zahra Zarei, Mozafar Bag‐Mohammadi
doaj +1 more source
Unions of Onions: Preprocessing Imprecise Points for Fast Onion Layer Decomposition [PDF]
, 2014 Let D be a set of n pairwise disjoint unit disks in the plane. We describe how to build a data structure for D so that for any point set P containing exactly one point from each disk, we can quickly nd the onion decomposition (convex layers) of P.
Sub Computational Geometry +3 more
core
Trajectory Grouping Structure under Geodesic Distance [PDF]
, 2015 Due to GPS and related technology, trajectory data has become one of the main types of geographic data, and algorithmic tools to handle large quantities of such data are essential.
Sub Computational Geometry +17 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Computational geometry for sculpture [PDF]
Proceedings of the seventeenth annual symposium on Computational geometry, 2001 This presentation illustrates examples of my geometric sculpture and o utlines certain design techniques. I apply methods from the field of computational geometry to the creation of forms which are aesthetic objects.I am a full- time sculptor creating works that manifest what I call the geometric aesthetic.
openaire +1 more source
Clear Unit-Distance Graphs [PDF]
, 2013 We introduce a variation of unit-distance graphs which we call emph clear unit-distance graphs. They require the pairwise distances of the representing points to be either exactly 1 or not close to 1.
Sub Computational Geometry +4 more
core
The Algebraic Revolution in Combinatorial and Computational Geometry: State of the Art (Invited Talk) [PDF]
, 2017 For the past 10 years, combinatorial geometry (and to some extent, computational geometry too) has gone through a dramatic revolution, due to the infusion of techniques from algebraic geometry and algebra that have proven effective in solving a variety ...
Sharir, Micha
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Current Open Problems in Discrete and Computational Geometry
Моделирование и анализ информационных систем, 2012 We have selected problems that may not yet be well known, but have the potential to push the research in interesting directions. In particular, we state problems that do not require specific knowledge outside the standard circle of ideas in discrete ...
H. Edelsbrunner, A. Ivanov, R. Karasev
doaj +3 more sources