Results 51 to 60 of about 815,076 (298)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Local and Global Approaches to Fracture Mechanics Using Isogeometric Analysis Method
Journal of Applied and Computational Mechanics, 2015 In the present research, implementations of different computational geometry technologies in isogeometric analysis framework for computational fracture mechanics are investigated.
Abdolghafoor Khademalrasoul, Reza Naderi
doaj +1 more source
Mathematics, 2020 Research on the rectangle packing problems has mainly focused on rectangular raw material sheets without defects, while natural slate has irregular and defective characteristics, and the existing packing method adopts manual packing, which wastes ...
Kaizhi Chen +3 more
doaj +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Multi-loop Integrand Reduction with Computational Algebraic Geometry
, 2013 We discuss recent progress in multi-loop integrand reduction methods. Motivated by the possibility of an automated construction of multi-loop amplitudes via generalized unitarity cuts we describe a procedure to obtain a general parameterisation of any ...
Badger, Simon +2 more
core +1 more source
COMPUTATIONAL GEOMETRY COLUMN 40
International Journal of Computational Geometry & Applications, 2000 It has recently been established by Below, De Loera, and Richter-Gebert that finding a minimum size (or even just a small) triangulation of a convex polyhedron is NP-complete. Their 3SAT-reduction proof is discussed.
openaire +3 more sources
International Journal of Adaptive Control and Signal Processing, EarlyView.This paper proposes two projector‐based Hopfield neural network (HNN) estimators for online, constrained parameter estimation under time‐varying data, additive disturbances, and slowly drifting physical parameters. The first is a constraint‐aware HNN that enforces linear equalities and inequalities (via slack neurons) and continuously tracks the ...
Miguel Pedro Silva
wiley +1 more source
International Conference “Geometry, Topology, and Applications”
Моделирование и анализ информационных систем, 2013 The International Conference on “Geometry, Topology, and Applications”, dedicated to the upcoming 70th birthday of Nikolai Dolbilin, was organized by the International Delaunay Laboratory on Discrete and Computational Geometry and took place in September
A. Garber +4 more
doaj +1 more source
Prime factorization using quantum annealing and computational algebraic geometry
, 2016 We investigate prime factorization from two perspectives: quantum annealing and computational algebraic geometry, specifically Gr\"obner bases. We present a novel scalable algorithm which combines the two approaches and leads to the factorization of all ...
Alghassi, Hedayat, Dridi, Raouf
core +1 more source