Results 71 to 80 of about 724,157 (279)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Ensemble deep learning-enabled single-shot composite structured illumination microscopy (eDL-cSIM)

open access: yesPhotoniX
Structured illumination microscopy (SIM) has emerged as a powerful super-resolution technique for studying protein dynamics in live cells thanks to its wide-field imaging mode and high photon efficiency.
Jiaming Qian   +4 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Fast Monte Carlo Simulation for Patient-specific CT/CBCT Imaging Dose Calculation

open access: yes, 2011
Recently, X-ray imaging dose from computed tomography (CT) or cone beam CT (CBCT) scans has become a serious concern. Patient-specific imaging dose calculation has been proposed for the purpose of dose management.
Briesmeister J F   +23 more
core   +1 more source

Single-shot compressed ultrafast photography: a review [PDF]

open access: yes, 2020
Compressed ultrafast photography (CUP) is a burgeoning single-shot computational imaging technique that provides an imaging speed as high as 10 trillion frames per second and a sequence depth of up to a few hundred frames.
Cao, Fengyan   +11 more
core  

Computer-assisted mammographic imaging [PDF]

open access: yesBreast Cancer Research, 2000
Computer-assisted mammography imaging comprises computer-based analysis of digitized images resulting in prompts aiding mammographic interpretation and computerized stereotactic localization devices which improve location accuracy. The commercial prompting systems available are designed to draw attention to mammographic abnormalities detected by ...
Boggis, Caroline RM, Astley, Susan M
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Unmanned Helicopter Airborne Fourier Transform Infrared Spectrometer Remote Sensing System for Hazardous Vapors Detection

open access: yesApplied Sciences
The rapid development of unmanned aerial vehicles (UAVs) provides a new application mode for gas remote sensing. Compared with fixed observation and vehicle-mounted platforms, a Fourier transform infrared spectrometer (FTIR) integrated in the UAV can ...
Zhengyang Shi   +5 more
doaj   +1 more source

Computational Imaging with Randomness

open access: yesFrontiers in Optics + Laser Science 2024 (FiO, LS), 2021
I will present our recent research efforts in computational imaging with randomness and scattering, including the use of machine learning techniques.
openaire   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

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