Results 71 to 80 of about 3,599,630 (258)

dO: A differentiable engine for Deep Lens design of computational imaging systems

, 2021
Computational imaging systems algorithmically post-process acquisition images either to reveal physical quantities of interest or to increase image quality, e.g., deblurring.
Wang, Congli, Heidrich, Wolfgang, Ni, Chen   +2 more
core   +1 more source

Ensemble deep learning-enabled single-shot composite structured illumination microscopy (eDL-cSIM)

PhotoniX
Structured illumination microscopy (SIM) has emerged as a powerful super-resolution technique for studying protein dynamics in live cells thanks to its wide-field imaging mode and high photon efficiency.
Jiaming Qian, Chunyao Wang, Hongjun Wu, Qian Chen, Chao Zuo   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Single shot approach for three-dimensional imaging with double-helix point spread functions

, 2022
Paper CTh1D.4A computational imaging approach based on engineered double-helix point spread functions is presented and tested experimentally. It enables the acquisition of threedimensional object information from a single shot by analyzing the image's ...
Berlich, R., Bräuer, A., Stallinga, S.
core   +1 more source

Transport-of-intensity diffraction tomography with nonuniform axial sampling (TIDT-NAS)

PhotoniX
Transport-of-intensity diffraction tomography (TIDT) extends the transport-of-intensity equation (TIE) from 2D phase retrieval to 3D refractive index (RI) tomography, enabling non-interferometric volumetric imaging under partially coherent illumination ...
Yefeng Shu, Jiasong Sun, Shun Zhou, Yao Fan, Anqi Tang, Wenzhuo Xie, Qingyang Fu, Mohammad Reza Zarei, Xiyu Chen, Xiaolei Zhang, Qian Chen, Chao Zuo   +11 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Digital Imaging Program fact sheet

, 2004
Title from PDF caption (viewed May 11, 2007).; "January 2004."; Previously issued: Fact sheet / Digital Imaging Program. [Hartford] : State of Connecticut, Dept. of Social Services, [1996]
Digital Imaging Program (Conn.)
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Unmanned Helicopter Airborne Fourier Transform Infrared Spectrometer Remote Sensing System for Hazardous Vapors Detection

Applied Sciences
The rapid development of unmanned aerial vehicles (UAVs) provides a new application mode for gas remote sensing. Compared with fixed observation and vehicle-mounted platforms, a Fourier transform infrared spectrometer (FTIR) integrated in the UAV can ...
Zhengyang Shi, Min Huang, Lulu Qian, Wei Han, Guifeng Zhang, Xiangning Lu   +5 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source