Results 31 to 40 of about 102,050 (305)

The theory of reasoned action as parallel constraint satisfaction: towards a dynamic computational model of health behavior. [PDF]

open access: yesPLoS ONE, 2013
The reasoned action approach, although ubiquitous in health behavior theory (e.g., Theory of Reasoned Action/Planned Behavior), does not adequately address two key dynamical aspects of health behavior: learning and the effect of immediate social context (
Mark G Orr   +2 more
doaj   +1 more source

The perceptions of information technology faculty students on online learning of computational mathematics during the covid-19 pandemic

open access: yesJurnal Math Educator Nusantara: Wahana Publikasi Karya Tulis Ilmiah di Bidang Pendidikan Matematika, 2021
The implementation of online learning in computational mathematics courses has encountered various obstacles in addition to the decline in student learning outcomes. Therefore, research is aimed to explore student perceptions of online learning that has
Filda Febrinita, Wahyu Dwi Puspitasari
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

ISAC Integration With Emerging Wireless Network Technologies: A Comprehensive Survey

open access: yesIEEE Open Journal of the Communications Society
Integrated Sensing and Communication (ISAC) has emerged as a fundamental paradigm for Sixth-Generation (6G) wireless networks, enabling the unified use of spectral and hardware resources for simultaneous data transmission and environmental sensing.
Mohamed S. Elbakry   +4 more
doaj   +1 more source

Efficient learning of a one-dimensional density functional theory

open access: yesPhysical Review Research, 2020
Density functional theory underlies the most successful and widely used numerical methods for electronic structure prediction of solids. However, it has the fundamental shortcoming that the universal density functional is unknown.
M. Michael Denner   +2 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

The computational thinking for science (CT-S) framework: operationalizing CT-S for K–12 science education researchers and educators

open access: yesInternational Journal of STEM Education, 2023
Contemporary science is a field that is becoming increasingly computational. Today’s scientists not only leverage computational tools to conduct their investigations, they often must contribute to the design of the computational tools for their specific ...
Timothy Hurt   +8 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Next-Gen UAV-Satellite Communications: AI Innovations and Future Prospects

open access: yesIEEE Open Journal of Vehicular Technology
The convergence of sixth-generation (6G) networks with unmanned aerial vehicles (UAVs) and satellites is poised to introduce substantial improvements to the landscape of wireless communication, paving the way for a unified and uninterrupted space-air ...
Sherief Hashima   +5 more
doaj   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel   +8 more
wiley   +1 more source

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