Results 51 to 60 of about 969,371 (282)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Recent Advances of Deep Learning in Bioinformatics and Computational Biology

Frontiers in Genetics, 2019
Extracting inherent valuable knowledge from omics big data remains as a daunting problem in bioinformatics and computational biology. Deep learning, as an emerging branch from machine learning, has exhibited unprecedented performance in quite a few ...
Binhua Tang, Binhua Tang, Zixiang Pan, Kang Yin, Asif Khateeb   +4 more
doaj   +1 more source

A Computational Theory of Learning Causal Relationships [PDF]

Cognitive Science, 1991
I present a cognitive model of the human ability to acquire causal relationships. I report on experimental evidence demonstrating that human learners acquire accurate causal relationships more rapidly when training examples are consistent with a general theory of causality.
openaire   +3 more sources

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +15 more
wiley   +1 more source

Effective deep learning aided vehicle classification approach using Seismic Data

Scientific Reports
Intelligent transportation systems (ITSs) significantly enhance traffic safety and management globally. A critical component of these systems is vehicle classification (VC), which supports vital applications such as congestion control, traffic monitoring,
Sherief Hashima, Mohamed H. Saad, Ahmad B. Ahmad, Takeshi Tsuji, Hamada Rizk   +4 more
doaj   +1 more source

Trajectories of Physical Function in Canadian Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objectives We describe trajectories of physical function in children newly diagnosed with juvenile idiopathic arthritis (JIA) and identify trajectories with persisting functional impairments and associated baseline characteristics. Methods We included patients enrolled in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry ...
Clare Cunningham, Meghan McPherson, Lillian Lim, Roberta A. Berard, Matthew Berkowitz, Jean‐Philippe Proulx‐Gauthier, Brian M. Feldman, Nicole Johnson, Dax G. Rumsey, Heinrike Schmeling, Lori B. Tucker, Thomas Loughin, Kristin M. Houghton, Jaime Guzman, The CAPRI Registry Investigators   +14 more
wiley   +1 more source

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

International Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam, Anthony Siming Chen, Guido Herrmann   +2 more
wiley   +1 more source

Physics computational literacy: An exploratory case study using computational essays

Physical Review Physics Education Research, 2019
Computation is becoming an increasingly important part of physics education. However, there are currently few theories of learning that can be used to help explain and predict the unique challenges and affordances associated with computation in physics ...
Tor Ole B. Odden, Elise Lockwood, Marcos D. Caballero   +2 more
doaj   +1 more source

Towards a general theory of neural computation based on prediction by single neurons. [PDF]

PLoS ONE, 2008
Although there has been tremendous progress in understanding the mechanics of the nervous system, there has not been a general theory of its computational function.
Christopher D Fiorillo
doaj   +1 more source

Social learning through associative processes: a computational theory

bioRxiv, 2018
Social transmission of information is a key phenomenon in the evolution of behavior and in the establishment of traditions and culture. The diversity of social learning phenomena has engendered a diverse terminology and numerous ideas about underlying ...
J. Lind, S. Ghirlanda, M. Enquist
semanticscholar   +1 more source