Results 101 to 110 of about 14,800,833 (304)
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Third Asian-Pacific Congress on Computational Mechanics and the Eleventh International Conference on the Enhancement and Promotion of Computational Methods in Engineering and Science國際20071203~20071206紙本YKyoto ...
Chen, C.-S.;Chang, S.-W.;Wang, C.-K.;Liao, Y.-P.;Huang, C.-W. +1 more
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Computational methods for analyzing and modeling gene regulation and 3D genome organization
Thesis: Ph. D., Massachusetts Institute of Technology, Computational and Systems Biology Program, February, 2021Cataloged from the official PDF of thesis.Includes bibliographical references (pages 261-281).Biological processes from differentiation to ...
Belyaeva, Anastasiya.
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MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Structural degradation assessment of a preheater tower in a cement plant in Peru
This article examines the structural behavior of a paradigmatic case in the cement industry: an existing reinforced concrete (RC) Preheater Tower (PT).
Paula Barboza +2 more
doaj +1 more source
Computational Methods in Structural Engineering: Current Advances and Future Perspectives
This brief editorial introduces the Special Issue “Computational Methods in Structural Engineering”. This Special Issue brings together recent advances in computational approaches—including finite element modeling, machine learning ...
Vagelis Plevris +2 more
core +1 more source
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Computational Fluid-Structure Interaction Methods and Applications
reference for researchers and practicing engineers who would like to advance their existing knowledge on these subjects. It is also an ideal text for graduate and senior-level undergraduate courses in computational fluid mechanics and computational ...
Bazilevs, Yuri +2 more
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