Results 91 to 100 of about 14,051,240 (304)

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

07411 Abstracts Collection – Algebraic Methods in Computational Complexity [PDF]

, 2008
From 07.10. to 12.10., the Dagstuhl Seminar 07411 ``Algebraic Methods in Computational Complexity'' was held in the International Conference and Research Center (IBFI), Schloss Dagstuhl. During the seminar, several participants presented their current
Agrawal, Manindra, Buhrman, Harry, Thierauf, Thomas, Fortnow, Lance   +3 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

04421 Abstracts Collection – Algebraic Methods in Computational Complexity [PDF]

, 2005
From 10.10.04 to 15.10.04, the Dagstuhl Seminar 04421 ``Algebraic Methods in Computational Complexity'' was held in the International Conference and Research Center (IBFI), Schloss Dagstuhl.
Buhrman, Harry, Thierauf, Thomas, Fortnow, Lance   +2 more
core   +1 more source

Force Transition between Atoms and Finite Elements in Quasicontinuum Method and Its Computational Implications

, 2015
Third Asian-Pacific Congress on Computational Mechanics and the Eleventh International Conference on the Enhancement and Promotion of Computational Methods in Engineering and Science國際20071203~20071206紙本YKyoto ...
Chen, C.-S.;Chang, S.-W.;Wang, C.-K.;Liao, Y.-P.;Huang, C.-W., Chen, C.-S.   +1 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Accurate numerical methods for studying the nonlinear wave-dynamics of tensegrity

, 2017
This paper presents presents an effective numerical approach to the nonlinear dynamics of columns of tensegrity prisms subject to impulsive compressive loading.
Penna R., Fabbrocino F., Carpentieri G., Amendola A., Fraternali, F.   +4 more
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Computational methods for splice site prediction [PDF]

, 2006
Taher L. Computational methods for splice site prediction. Bielefeld (Germany): Bielefeld University; 2006.Completing the genome sequence of a given organism is just the beginning of a series of subsequent tasks, namely, the discovery of the ...
Taher, Leila
core