Results 91 to 100 of about 14,800,833 (304)
EnergiesClimate change and global decarbonization targets drive the search for more efficient and cost-effective combustion technologies. Chemical looping combustion (CLC) using solid oxygen carriers with chemical looping with oxygen uncoupling (CLOU ...
Anna Zylka +6 more
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Computational Methods for Differential Equations
The CMDE journal (Computational Methods for Differential Equations) aims to publish original research articles related to the development and analysis of new methods for solving differential equations, and their numerical or computational ...
Ballestra Luca Vincenzo
core +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
A Smart Data Hub to integrate subsurface properties into model-based decision-support tools
Scientific DataThe selection of suitable nuclear waste disposal sites is a long and challenging process, involving multiple technical and environmental assessments. For data-integrated simulation models to function as credible decision-support tools in this sensitive ...
Qian Chen +3 more
doaj +1 more source
Superconducting TaH5 at high pressure
New Journal of Physics, 2019 Recently, the significant development, in the field of high-temperature superconductivity among the compressed elements hydrides (such as LaH _10 ), opens up a door in pursuing room-temperature superconductors.
Hefei Li +5 more
doaj +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
MOLECULAR ORDER AND DYNAMICS OF 5CB LIQUID CRYSTALS IN CONFINED SPACE – COMPUTER SIMULATION
TASK Quarterly, 2015 We studied the dynamical and structural properties of an important nematic 4-n-pentyl-4’-cyanobiphenyl (5CB) mesogen placed near carbon allotropes (graphene, nanotube), using modeling and molecular dynamics simulations (MD).
W. GWIZDAŁA, Z. GBURSKI
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source