Results 71 to 80 of about 14,800,833 (304)

A posteriori error estimation for model order reduction of parametric systems

Advanced Modeling and Simulation in Engineering Sciences
This survey discusses a posteriori error estimation for model order reduction of parametric systems, including linear and nonlinear, time-dependent and steady systems.
Lihong Feng, Sridhar Chellappa, Peter Benner   +2 more
doaj   +1 more source

04421 Abstracts Collection – Algebraic Methods in Computational Complexity [PDF]

, 2005
From 10.10.04 to 15.10.04, the Dagstuhl Seminar 04421 ``Algebraic Methods in Computational Complexity'' was held in the International Conference and Research Center (IBFI), Schloss Dagstuhl.
Buhrman, Harry, Thierauf, Thomas, Fortnow, Lance   +2 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Segmentation of Foreground Row Trees in Apple Orchard Images Collected by Ground Vehicles [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences
This paper proposes a fully automatic method for the segmentation of foreground row trees in industrial apple orchard images. The segmentation is based on analyzing a combination of a depth map constructed by the Marigold diffusion model and a model ...
M. A. Merzliakova, B. M. Shurygin, A. E. Solovchenko, A. S. Krylov, D. V. Sorokin   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Pairwise ratio transformation of gene expression data leads to improved checkpoint response prediction in lung cancer patients

BMC Bioinformatics
Background Machine learning algorithms identify patterns that would otherwise be difficult to observe in high-dimensional molecular and clinical data.
Jacob Pfeil, Liqian Ma, Hin Ching Lo, Tolga Turan, R. Tyler McLaughlin, Xu Shi, Severiano Villarruel, Stephen Wilson, Xi Zhao, Josue Samayoa, Kyle Halliwill   +10 more
doaj   +1 more source

The Southern Annular Mode and Southern Ocean Surface Westerly Winds in E3SM

Earth and Space Science, 2019
Climate variability and change in the Southern Hemisphere (SH) are influenced by the Southern Annular Mode (SAM) and are closely related to changes in the kinematic properties of the SH surface zonal winds.
Doo Young Lee, Mark R. Petersen, Wuyin Lin   +2 more
doaj   +1 more source

09421 Abstracts Collection – Algebraic Methods in Computational Complexity [PDF]

, 2010
From 11.10. to 16.10.2009, the Dagstuhl Seminar 09421 ``Algebraic Methods in Computational Complexity '' was held in Schloss Dagstuhl~--~Leibniz Center for Informatics.
Agrawal, Manindra, Umans, Christopher, Thierauf, Thomas, Fortnow, Lance   +3 more
core   +1 more source

Ribosomal computing: implementation of the computational method

BMC Bioinformatics
Several computational and mathematical models of protein synthesis have been explored to accomplish the quantitative analysis of protein synthesis components and polysome structure. The effect of gene sequence (coding and non-coding region) in protein synthesis, mutation in gene sequence, and functional model of ribosome needs to be explored to ...
Pratima Chatterjee, Prasun Ghosal, Sahadeb Shit, Arindam Biswas 0007, Saurav Mallik, Sarah Allabun, Manal Othman, Almubarak Hassan Ali, E. Elshiekh, Ben Othman Soufiene   +9 more
openaire   +4 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source