Results 71 to 80 of about 3,015,044 (288)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

The computational complexity of traditional Lattice-Boltzmann methods for incompressible fluids

, 2008
It is well-known that in fluid dynamics an alternative to customary direct solution methods (based on the discretization of the fluid fields) is provided by so-called \emph{particle simulation methods}.
Enrico Fonda, Marco Tessarotto, Massimo Tessarotto, Takashi Abe   +3 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Improving CO₂ Capture Efficiency Through Novel CLOU-Based Fuel Reactor Configuration in Chemical Looping Combustion

Energies
Climate change and global decarbonization targets drive the search for more efficient and cost-effective combustion technologies. Chemical looping combustion (CLC) using solid oxygen carriers with chemical looping with oxygen uncoupling (CLOU ...
Anna Zylka, Jaroslaw Krzywanski, Tomasz Czakiert, Marcin Sosnowski, Karolina Grabowska, Dorian Skrobek, Lukasz Lasek   +6 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Characterization and frequency analysis of flooding solid flow in semi-arid zone: case of Mekerra catchment in the north-west of Algeria

Applied Water Science, 2020
In this study, we evaluate the soil erosion and solid transport in the oued Mekerra watershed in north-west Algeria. The study area is subject to a semi-arid climate characterized by irregular rainfall and showers, which are often accompanied by ...
M. Diaf, A. Hazzab, A. Yahiaoui, A. Belkendil   +3 more
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Superconducting TaH5 at high pressure

New Journal of Physics, 2019
Recently, the significant development, in the field of high-temperature superconductivity among the compressed elements hydrides (such as LaH _10 ), opens up a door in pursuing room-temperature superconductors.
Hefei Li, Xue Li, Hui Wang, Guangtao Liu, Yinwei Li, Hanyu Liu   +5 more
doaj   +1 more source

Integrand-Level Reduction of Loop Amplitudes by Computational Algebraic Geometry Methods

, 2012
We present an algorithm for the integrand-level reduction of multi-loop amplitudes of renormalizable field theories, based on computational algebraic geometry.
Zhang, Yang
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source