Results 31 to 40 of about 3,015,044 (288)

GeFaST: An improved method for OTU assignment by generalising Swarm’s fastidious clustering approach

BMC Bioinformatics, 2018
Background Massive genomic data sets from high-throughput sequencing allow for new insights into complex biological systems such as microbial communities. Analyses of their diversity and structure are typically preceded by clustering millions of 16S rRNA
Robert Müller, Markus E. Nebel
doaj   +1 more source

Computational methods for Bayesian model choice

, 2009
In this note, we shortly survey some recent approaches on the approximation of the Bayes factor used in Bayesian hypothesis testing and in Bayesian model choice.
C. P. Robert, Chun-Yong Chan, D. Wraith, Paul M. Goggans   +3 more
core   +4 more sources

The Computational Diet: A Review of Computational Methods Across Diet, Microbiome, and Health. [PDF]

, 2020
Food and human health are inextricably linked. As such, revolutionary impacts on health have been derived from advances in the production and distribution of food relating to food safety and fortification with micronutrients. During the past two decades,
Eetemadi, Ameen, Kim, Minseung, Pereira, Beatriz Merchel Piovesan, Rai, Navneet, Schmitz, Harold, Tagkopoulos, Ilias   +5 more
core  

Computational methods for finding long simple cycles in complex networks [PDF]

, 2017
© 2017 Elsevier B.V. Detection of long simple cycles in real-world complex networks finds many applications in layout algorithms, information flow modelling, as well as in bioinformatics.
Balaghan, Phininder, Chalupa, David, Gordon, Neil A., Hawick, Ken A.   +3 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Essential guidelines for computational method benchmarking [PDF]

, 2019
In computational biology and other sciences, researchers are frequently faced with a choice between several computational methods for performing data analyses. Benchmarking studies aim to rigorously compare the performance of different methods using well-
Boulesteix, Anne-Laure, Cannoodt, Robrecht, Gardner, Paul P, Hapfelmeier, Alexander, Robinson, Mark D, Saelens, Wouter, Saeys, Yvan, Soneson, Charlotte, Weber, Lukas M   +8 more
core   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Reusability-targeted enrichment of sea ice core data

Scientific Data
The Reusability-targeted Enriched Sea Ice Core Database (RESICE) combines data and metadata from 287 sea ice cores. The database enables reuse scenarios such as the validation of physics-based models and the training of data-driven algorithms.
Anna Simson, Anil Yildiz, Julia Kowalski
doaj   +1 more source

EVALUATION OF ACQUISITION STRATEGIES FOR IMAGE-BASED CONSTRUCTION SITE MONITORING [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2016
Construction site monitoring is an essential task for keeping track of the ongoing construction work and providing up-to-date information for a Building Information Model (BIM).
S. Tuttas, S. Tuttas, A. Braun, A. Braun, A. Borrmann, A. Borrmann, U. Stilla, U. Stilla   +7 more
doaj   +1 more source