Results 41 to 50 of about 1,176,061 (314)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Reusability-targeted enrichment of sea ice core data

Scientific Data
The Reusability-targeted Enriched Sea Ice Core Database (RESICE) combines data and metadata from 287 sea ice cores. The database enables reuse scenarios such as the validation of physics-based models and the training of data-driven algorithms.
Anna Simson, Anil Yildiz, Julia Kowalski
doaj   +1 more source

EVALUATION OF ACQUISITION STRATEGIES FOR IMAGE-BASED CONSTRUCTION SITE MONITORING [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2016
Construction site monitoring is an essential task for keeping track of the ongoing construction work and providing up-to-date information for a Building Information Model (BIM).
S. Tuttas, S. Tuttas, A. Braun, A. Braun, A. Borrmann, A. Borrmann, U. Stilla, U. Stilla   +7 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Data-driven prediction of complex crystal structures of dense lithium

Nature Communications, 2023
Lithium (Li) is a prototypical simple metal at ambient conditions, but exhibits remarkable changes in structural and electronic properties under compression.
Xiaoyang Wang, Zhenyu Wang, Pengyue Gao, Chengqian Zhang, Jian Lv, Han Wang, Haifeng Liu, Yanchao Wang, Yanming Ma   +8 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Computational Methods in Economic Dynamics [PDF]

, 2011
Dawid H, Semmler W, eds. Computational Methods in Economic Dynamics.
LICALZI M, LI CALZI, Marco, He, X, Marco LiCalzi, Shi, L, Dawid, Herbert ; https://orcid.org/, PELLIZZARI, Paolo, MILONE L, Lei Shi, PELLIZZARI P, Lucia Milone, Paolo Pellizzari, MILONE, Lucia, Xue-Zhong He, Semmler, Willi   +14 more
core   +1 more source

Nucleophilicity Index Based on Atomic Natural Orbitals

Journal of Chemistry, 2013
A simple method of evaluating a semilocal (regional) nucleophilicity is introduced. The concept involves use of the natural orbitals for atomic populations to identify the most “reactive population” of electrons on particular atom in molecule.
Dariusz W. Szczepanik, Janusz Mrozek
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

PREPROCESSING AND REGISTRATION OF MINISCOPE-BASED CALCIUM IMAGING OF THE RODENT BRAIN [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019
Microscopic imaging is central to the brain and cognition studies in animals and often requires advanced image processing. In vivo recordings on awake behaving animals require stabilization of the images as the tissue in the images undergoes non-rigid ...
T. B. Sagindykov, A. R. Brazhe, D. V. Sorokin   +2 more
doaj   +1 more source