Results 81 to 90 of about 161,334 (315)

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Agent-Based Computational Economics [PDF]

Agent-based computational economics (ACE) is the computational study of economies modeled as evolving systems of autonomous interacting agents. Starting from initial conditions, specified by the modeler, the computational economy evolves over time as its
Leigh Tesfatsion
core  

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

High Performance Numerical Computing for High Energy Physics: A New Challenge for Big Data Science

Advances in High Energy Physics, 2014
Modern physics is based on both theoretical analysis and experimental validation. Complex scenarios like subatomic dimensions, high energy, and lower absolute temperature are frontiers for many theoretical models. Simulation with stable numerical methods
Florin Pop
doaj   +1 more source

Preliminary specification and design documentation for software components to achieve catallaxy in computational systems [PDF]

This Report is about the preliminary specifications and design documentation for software components to achieve Catallaxy in computational systems. -- Die Arbeit beschreibt die Spezifikation und das Design von Softwarekomponenten, um das Konzept der ...
Veit, Daniel, Streitberger, Werner, Freitag, Felix, Eymann, Torsten, Chao, Isaac, Reinicke, Michael, Chacin, Pablo, Schnizler, Björn   +7 more
core  

Discrete exterior geometry approach to structure-preserving discretization of distributed-parameter port-Hamiltonian systems [PDF]

, 2011
This paper addresses the issue of structure-preserving discretization of open distributed-parameter systems with Hamiltonian dynamics. Employing the formalism of discrete exterior calculus, we introduce a simplicial Dirac structure as a discrete analogue
Seslija, Marko,, Scherpen, Jacquelien M.A.,, van der Schaft, Abraham, van der Schaft, Abraham; id_orcid, Arjan Van Der Schaft, Jacquelien M. A. Scherpen, van der Schaft, Arjan, Scherpen, Jacquelien M.A., Seslija, Marko, van der Schaft, Arjan ; id_orcid, Marko Seslija, Schaft, Arjan van der,   +11 more
core   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Bayesian computational methods [PDF]

If, in the mid 1980?s, one had asked the average statistician about the difficulties of using Bayesian Statistics, his/her most likely answer would have been ?Well, there is this problem of selecting a prior distribution and then, even if one agrees on ...
Robert, Christian P.
core  

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Formal Methods Unifying Computing Science and Systems Theory

Journal of Systemics, Cybernetics and Informatics, 2004
Computing Science and Systems Theory can gain much from unified mathematical models and methodology, in particular formal reasoning ("letting the symbols do the work"). This is achieved by a wide-spectrum formalism. The language uses just four constructs, yet suffices to synthesize familiar notations (minus the defects) as well as new ones. It supports
openaire   +4 more sources