Results 91 to 100 of about 3,156,569 (293)
Geo-spatial Information ScienceAutonomous navigation plays a crucial role in cutting-edge scientific and technological domains, such as autonomous driving and space exploration. Current models often rely on knowledge of the discharge patterns of navigation cells in living organisms (e.
Donghui Han +7 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
A computational model for a regenerator [PDF]
This paper concerns a numerical model of a regenerator running at very low temperatures. The model consists of the usual three equations for a compressible fluid with an additional equation for a matrix temperature.
Daney, D. E., Gary, J., Radebaugh, R.
core +1 more source
Computational study of structural and elastic properties of random AlGaInN alloys
, 2010 In this work we present a detailed computational study of structural and elastic properties of cubic AlGaInN alloys in the framework of Keating valence force field model, for which we perform accurate parametrization based on state of the art DFT ...
Ambacher O +9 more
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
A Computational Model of Worker Protest [PDF]
This paper presents an agent-based model of worker protest. Workers have varying degrees of grievance depending on the difference between their wage and the average of their neighbors.
Jae-Woo Kim, Robert Hanneman
core
ASR decoding in a computational model of human word recognition [PDF]
, 2005 This paper investigates the interaction between acoustic scores and symbolic mismatch penalties in multi-pass speech decoding techniques that are based on the creation of a segment graph followed by a lexical search.
Scharenborg, O., ten Bosch, L.
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source