Results 21 to 30 of about 26,598,097 (313)

Typologies of Computation and Computational Models

CoRR, 2013
We need much better understanding of information processing and computation as its primary form. Future progress of new computational devices capable of dealing with problems of big data, internet of things, semantic web, cognitive robotics and neuroinformatics depends on the adequate models of computation.
Mark Burgin, Gordana Dodig-Crnkovic
openaire   +2 more sources

The Nature of Computational Models

Computing in Science & Engineering, 2023
Computational models lie at the heart of computational science. And yet, few scientists have a clear idea of what a computational model actually is. Is it software? Or an algorithm? How does it relate to mathematical models? What are suitable languages or notations for expressing a computational model in the literature?
openaire   +2 more sources

Computer modelling of monoamine oxidases [PDF]

Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry, 2015
The article summarized results of studies on active site structures of monoamine oxidases (MAO) performed in the Institute of Biomedical Chemistry (Russia) by computer modelling approaches. MAO, catalyzing the reaction of oxidative deamination of major neurotransmitter monoamines, exists in two highly homologous forms, MAO A and MAO B, distinguished by
A V, Veselovsky, A S, Ivanov, A E, Medvedev   +2 more
openaire   +2 more sources

A Whole-Cell Computational Model Predicts Phenotype from Genotype

Cell, 2012
SUMMARY Understanding how complex phenotypes arise from individual molecules and their interactions is a primary challenge in biology that computational approaches are poised to tackle.
Jonathan R. Karr, Jayodita C. Sanghvi, Derek N. Macklin, Miriam V. Gutschow, J. M. Jacobs, Benjamin Bolival, N. Assad-Garcia, J. Glass, M. Covert   +8 more
semanticscholar   +1 more source

Neuronal and Astrocytic Regulations in Schizophrenia: A Computational Modelling Study

Frontiers in Cellular Neuroscience, 2021
According to the tripartite synapse model, astrocytes have a modulatory effect on neuronal signal transmission. More recently, astrocyte malfunction has been associated with psychiatric diseases such as schizophrenia.
Lea Fritschi, Johanna Hedlund Lindmar, Florian Scheidl, Kerstin Lenk, Kerstin Lenk   +4 more
doaj   +1 more source

Development and Validation of a Computational Model for Androgen Receptor Activity

Chemical Research in Toxicology, 2016
Testing thousands of chemicals to identify potential androgen receptor (AR) agonists or antagonists would cost millions of dollars and take decades to complete using current validated methods.
N. Kleinstreuer, P. Ceger, Eric D Watt, Matt T. Martin, K. Houck, P. Browne, Russell S. Thomas, W. Casey, D. Dix, D. Allen, S. Sakamuru, M. Xia, Ruili Huang, R. Judson   +13 more
semanticscholar   +1 more source

Diffusion models in bioinformatics and computational biology

Nature Reviews Bioengineering, 2023
Denoising diffusion models embody a type of generative artificial intelligence that can be applied in computer vision, natural language processing and bioinformatics.
Zhiye Guo, Jian Liu, Yanli Wang, Mengrui Chen, Duolin Wang, Dong Xu, Jianlin Cheng   +6 more
semanticscholar   +1 more source

TMS-evoked responses are driven by recurrent large-scale network dynamics

eLife, 2023
A compelling way to disentangle the complexity of the brain is to measure the effects of spatially and temporally synchronized systematic perturbations.
Davide Momi, Zheng Wang, John D Griffiths   +2 more
doaj   +1 more source

Volume changes at Santiaguito volcano between 2011 and 2019 based on TanDEM-X InSAR data

Frontiers in Earth Science
The Santiaguito volcanic dome complex in Guatemala consists of four volcanic domes formed within the 1902 eruption crater of Santa María volcano, with only the oldest dome, Caliente, currently active.
Ann-Kathrin Edrich, Ann-Kathrin Edrich, Julia Kubanek, Ellen Gottschämmer, Alexandra Duckstein, Malte Westerhaus, Julia Kowalski, Andreas Rietbrock   +7 more
doaj   +1 more source

A practical introduction to using the drift diffusion model of decision-making in cognitive psychology, neuroscience, and health sciences

Frontiers in Psychology, 2022
Recent years have seen a rapid increase in the number of studies using evidence-accumulation models (such as the drift diffusion model, DDM) in the fields of psychology and neuroscience. These models go beyond observed behavior to extract descriptions of
Catherine E. Myers, Catherine E. Myers, Alejandro Interian, Alejandro Interian, Ahmed A. Moustafa, Ahmed A. Moustafa   +5 more
doaj   +1 more source