Results 31 to 40 of about 15,734,175 (308)
Computer modelling of monoamine oxidases [PDF]
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry, 2015 The article summarized results of studies on active site structures of monoamine oxidases (MAO) performed in the Institute of Biomedical Chemistry (Russia) by computer modelling approaches. MAO, catalyzing the reaction of oxidative deamination of major neurotransmitter monoamines, exists in two highly homologous forms, MAO A and MAO B, distinguished by
A V, Veselovsky +2 more
openaire +2 more sources
Computational modeling of epilepsy [PDF]
Epilepsia, 2011 SummaryWith the rapid rise in our knowledge about the structural and functional properties of neuronal microcircuits and the exponentially increasing power of computers, it has become possible to closely integrate experimental findings with large‐scale, anatomically and biophysically realistic computational simulations of control and epileptic neuronal
Marianne, Case, Ivan, Soltesz
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Neuronal and Astrocytic Regulations in Schizophrenia: A Computational Modelling Study
Frontiers in Cellular Neuroscience, 2021 According to the tripartite synapse model, astrocytes have a modulatory effect on neuronal signal transmission. More recently, astrocyte malfunction has been associated with psychiatric diseases such as schizophrenia.
Lea Fritschi +4 more
doaj +1 more source
TMS-evoked responses are driven by recurrent large-scale network dynamics
eLife, 2023 A compelling way to disentangle the complexity of the brain is to measure the effects of spatially and temporally synchronized systematic perturbations.
Davide Momi +2 more
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Frontiers in Psychology, 2022 Recent years have seen a rapid increase in the number of studies using evidence-accumulation models (such as the drift diffusion model, DDM) in the fields of psychology and neuroscience. These models go beyond observed behavior to extract descriptions of
Catherine E. Myers +5 more
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Reusability-targeted enrichment of sea ice core data
Scientific DataThe Reusability-targeted Enriched Sea Ice Core Database (RESICE) combines data and metadata from 287 sea ice cores. The database enables reuse scenarios such as the validation of physics-based models and the training of data-driven algorithms.
Anna Simson, Anil Yildiz, Julia Kowalski
doaj +1 more source
Volume changes at Santiaguito volcano between 2011 and 2019 based on TanDEM-X InSAR data
Frontiers in Earth ScienceThe Santiaguito volcanic dome complex in Guatemala consists of four volcanic domes formed within the 1902 eruption crater of Santa María volcano, with only the oldest dome, Caliente, currently active.
Ann-Kathrin Edrich +7 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Computational model of the human urinary blader [PDF]
, 2013 The proposal of an artificial bladder is still a challenge to overcome. Bladder cancer is among the most frequent cases of oncologic diseases in United States and Europe.
Monteiro, Virginia Silva Araujo +2 more
core +1 more source
Phase separation of competing memories along the human hippocampal theta rhythm
eLife, 2022 Competition between overlapping memories is considered one of the major causes of forgetting, and it is still unknown how the human brain resolves such mnemonic conflict.
Casper Kerrén +3 more
doaj +1 more source