Results 51 to 60 of about 26,976,188 (312)
A Smart Data Hub to integrate subsurface properties into model-based decision-support tools
Scientific DataThe selection of suitable nuclear waste disposal sites is a long and challenging process, involving multiple technical and environmental assessments. For data-integrated simulation models to function as credible decision-support tools in this sensitive ...
Qian Chen +3 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
The ADaptation and Anticipation Model (ADAM) of sensorimotor synchronization
Frontiers in Human Neuroscience, 2013 A constantly changing environment requires precise yet flexible timing of movements. Sensorimotor synchronization (SMS) —the temporal coordination of an action with events in a predictable external rhythm— is a fundamental human skill that contributes to
Maria Christine Van Der Steen +2 more
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SWISS-MODEL: homology modelling of protein structures and complexes
Nucleic Acids Res., 2018 Homology modelling has matured into an important technique in structural biology, significantly contributing to narrowing the gap between known protein sequences and experimentally determined structures. Fully automated workflows and servers simplify and
A. Waterhouse +11 more
semanticscholar +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A DNA computing inspired computational model
Theoretical Computer Science, 2008 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
FRANCO, Giuditta, M. Margenstern
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
On Models of a Nondeterministic Computation [PDF]
, 2009 In this paper we consider a nondeterministic computation by deterministic multi-head 2-way automata having a read-only access to an auxiliary memory. The memory contains additional data (a guess) and computation is successful iff it is successful for some memory content.
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source