Results 31 to 40 of about 297,450 (276)

From cognitive science to cognitive neuroscience to neuroeconomics [PDF]

, 2008
As an emerging discipline, neuroeconomics faces considerable methodological and practical challenges. In this paper, I suggest that these challenges can be understood by exploring the similarities and dissimilarities between the emergence of ...
Quartz, Steven R.
core   +1 more source

Context-sensitive computational mechanistic explanation in cognitive neuroscience

Frontiers in Psychology, 2022
Mainstream cognitive neuroscience aims to build mechanistic explanations of behavior by mapping abilities described at the organismal level via the subpersonal level of computation onto specific brain networks.
Matthieu M. de Wit, Heath E. Matheson
doaj   +1 more source

Dynamics of large-scale neuronal networks of the human cortex functional connectivity : From Twenty First Annual Computational Neuroscience Meeting: CNS*2012 Decatur, GA, USA. 21-26 July 2012 [PDF]

, 2012
Published by BioMed Central Vuksanović, Vesna ; Hövel, Philipp : Dynamics of large-scale neuronal networks of the human cortex functional connectivity : From Twenty First Annual Computational Neuroscience Meeting: CNS*2012 Decatur, GA, USA.
Hövel, Philipp, Vuksanović, Vesna
core   +1 more source

The Interplay of Synaptic Plasticity and Scaling Enables Self-Organized Formation and Allocation of Multiple Memory Representations

Frontiers in Neural Circuits, 2020
It is commonly assumed that memories about experienced stimuli are represented by groups of highly interconnected neurons called cell assemblies. This requires allocating and storing information in the neural circuitry, which happens through synaptic ...
Johannes Maria Auth, Johannes Maria Auth, Timo Nachstedt, Timo Nachstedt, Christian Tetzlaff, Christian Tetzlaff   +5 more
doaj   +1 more source

Neurophysiology and computational neuroscience [PDF]

Experimental Brain Research, 2010
Issues 3–4 of the 200th volume of Experimental Brain Research are devoted to neurophysiology and computational neuroscience. Neurophysiology has remained a major focus of Experimental Brain Research since the founding of the journal in 1966 by an editorial board that included Sir John Eccles.
John C, Rothwell, R, Shadmehr, B, Yates
openaire   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The Hidden Brain: Uncovering Previously Overlooked Brain Regions by Employing Novel Preclinical Unbiased Network Approaches

Frontiers in Systems Neuroscience, 2021
A large focus of modern neuroscience has revolved around preselected brain regions of interest based on prior studies. While there are reasons to focus on brain regions implicated in prior work, the result has been a biased assessment of brain function ...
Sierra Simpson, Yueyi Chen, Yueyi Chen, Emma Wellmeyer, Lauren C. Smith, Brianna Aragon Montes, Olivier George, Adam Kimbrough, Adam Kimbrough, Adam Kimbrough   +9 more
doaj   +1 more source

KInNeSS: A Modular Framework for Computational Neuroscience [PDF]

, 2007
Making use of very detailed neurophysiological, anatomical, and behavioral data to build biological-realistic computational models of animal behavior is often a difficult task.
Ames, Heather, Fontenberry, Bret, Gorchetchnikov, Anatoli, Léveillé, Jasmin, Versace, Massimiliano   +4 more
core   +2 more sources

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Neuromodulator-dependent synaptic tagging and capture retroactively controls neural coding in spiking neural networks

Scientific Reports, 2022
Events that are important to an individual’s life trigger neuromodulator release in brain areas responsible for cognitive and behavioral function. While it is well known that the presence of neuromodulators such as dopamine and norepinephrine is required
Andrew B. Lehr, Jannik Luboeinski, Christian Tetzlaff   +2 more
doaj   +1 more source