Results 41 to 50 of about 2,017,547 (269)

Context-sensitive computational mechanistic explanation in cognitive neuroscience

Frontiers in Psychology, 2022
Mainstream cognitive neuroscience aims to build mechanistic explanations of behavior by mapping abilities described at the organismal level via the subpersonal level of computation onto specific brain networks.
Matthieu M. de Wit, Heath E. Matheson
doaj   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

The Interplay of Synaptic Plasticity and Scaling Enables Self-Organized Formation and Allocation of Multiple Memory Representations

Frontiers in Neural Circuits, 2020
It is commonly assumed that memories about experienced stimuli are represented by groups of highly interconnected neurons called cell assemblies. This requires allocating and storing information in the neural circuitry, which happens through synaptic ...
Johannes Maria Auth, Johannes Maria Auth, Timo Nachstedt, Timo Nachstedt, Christian Tetzlaff, Christian Tetzlaff   +5 more
doaj   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source

Toward stressor-free stress estimation: The integrated information theory explains the information dynamics of stress

iScience
Summary: Recent neurological studies have revealed several detailed stress mechanisms. However, the latent variables behind stress study still interpret stress responses as difficult.
Takayuki Niizato, Yuta Nishiyama, Yuta Oka, Poe Thinzar Aung, Shusaku Nomura   +4 more
doaj   +1 more source

Unexpected complexity of everyday manual behaviors

Nature Communications, 2020
How does the brain control the complex movements of hands? Here, by tracking human hand kinematics and applying multidimensional reduction techniques, the authors provide evidence that grasping involves a complex control system that regulates even the ...
Yuke Yan, James M. Goodman, Dalton D. Moore, Sara A. Solla, Sliman J. Bensmaia   +4 more
doaj   +1 more source

The Hidden Brain: Uncovering Previously Overlooked Brain Regions by Employing Novel Preclinical Unbiased Network Approaches

Frontiers in Systems Neuroscience, 2021
A large focus of modern neuroscience has revolved around preselected brain regions of interest based on prior studies. While there are reasons to focus on brain regions implicated in prior work, the result has been a biased assessment of brain function ...
Sierra Simpson, Yueyi Chen, Yueyi Chen, Emma Wellmeyer, Lauren C. Smith, Brianna Aragon Montes, Olivier George, Adam Kimbrough, Adam Kimbrough, Adam Kimbrough   +9 more
doaj   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi, Giorgio Ricciardiello Mejia, Andre Metzger, Kang Hyun Ryu, Salonee Marwaha, Eva Grzegorczyk, Li Zhou, Eliana Jacobs, Boris Gilyadov, Claudia Kunney, Liqhwa Ncube, Ankit Parekh, Emmanuel Mignot, Fanny M. Elahi, Joseph Winer, Kathleen Poston, Andreas Brink‐Kjaer, Emmanuel H. During   +17 more
wiley   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Decoding the ERD/ERS: influence of afferent input induced by a leg assistive robot

Frontiers in Systems Neuroscience, 2014
This paper investigates the influence of the leg afferent input, induced by a leg assistive robot, on the decoding performance of a BMI system. Specifically, it focuses on a decoder based on the event-related (de)synchronization (ERD/ERS) of the ...
Giuseppe eLisi, Giuseppe eLisi, Tomoyuki eNoda, Jun eMorimoto   +3 more
doaj   +1 more source