Results 51 to 60 of about 2,017,547 (269)

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

COMPUTATIONAL NEUROSCIENCE FOR ADVANCING ARTIFICIAL INTELLIGENCE

open access: yesCuadernos de Neuropsicología, 2011
resumen del libro de Alonso, E. y Mondragón, E. (2011). Hershey, NY: Medical Information Science Reference. La neurociencia como disciplinapersigue el entendimiento del cerebro y su relación con el funcionamiento de la mente a través del análisis de la ...
Fernando P. Ponce
doaj   +2 more sources

Visualizing and quantifying movement from pre-recorded videos: The spectral time-lapse (STL) algorithm [v1; ref status: indexed, http://f1000r.es/2qo]

open access: yesF1000Research, 2014
When studying animal behaviour within an open environment, movement-related data are often important for behavioural analyses. Therefore, simple and efficient techniques are needed to present and analyze the data of such movements.
Christopher R Madan, Marcia L Spetch
doaj   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park   +5 more
wiley   +1 more source

Towards Explainable Deep Learning in Computational Neuroscience: Visual and Clinical Applications

open access: yesMathematics
Deep learning has emerged as a powerful tool in computational neuroscience, enabling the modeling of complex neural processes and supporting data-driven insights into brain function. However, the non-transparent nature of many deep learning models limits
Asif Mehmood   +2 more
doaj   +1 more source

Equilibrium and response properties of the integrate-and-fire neuron in discrete time

open access: yesFrontiers in Computational Neuroscience, 2010
The integrate-and-fire neuron with exponential postsynaptic potentials is a frequently employed model to study neural networks. Simulations in discrete time still have highest performance at moderate numerical errors, which makes them first choice for ...
Moritz Helias   +8 more
doaj   +1 more source

Neuroscience Needs Network Science [PDF]

open access: yes, 2023
The brain is a complex system comprising a myriad of interacting neurons, posing significant challenges in understanding its structure, function, and dynamics.
Bullmore, E   +39 more
core   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

Reproducing asymmetrical spine shape fluctuations in a model of actin dynamics predicts self-organized criticality

open access: yesScientific Reports, 2021
Dendritic spines change their size and shape spontaneously, but the function of this remains unclear. Here, we address this in a biophysical model of spine fluctuations, which reproduces experimentally measured spine fluctuations.
Mayte Bonilla-Quintana   +4 more
doaj   +1 more source

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