Results 51 to 60 of about 126,855 (275)

The Interplay of Synaptic Plasticity and Scaling Enables Self-Organized Formation and Allocation of Multiple Memory Representations

Frontiers in Neural Circuits, 2020
It is commonly assumed that memories about experienced stimuli are represented by groups of highly interconnected neurons called cell assemblies. This requires allocating and storing information in the neural circuitry, which happens through synaptic ...
Johannes Maria Auth, Johannes Maria Auth, Timo Nachstedt, Timo Nachstedt, Christian Tetzlaff, Christian Tetzlaff   +5 more
doaj   +1 more source

A P300-Based Brain-Robot Interface for Shaping Human-Robot Interaction. Frontiers in Computational Neuroscience

, 2009
Finke A, Jin Y, Ritter H. A P300-Based Brain-Robot Interface for Shaping Human-Robot Interaction. Frontiers in Computational Neuroscience.
Finke, A, Jin, Yaochu, Ritter, Helge ; https://orcid.org/, Jin, Y, Finke, Andrea ; https://orcid.org/, Ritter, H   +5 more
core   +1 more source

Representations of Sensory Signals and Abstract Categories in Brain Networks

, 2021
Many recent advances in artificial intelligence (AI) are rooted in visual neuroscience. However, ideas from more complicated paradigms like decision-making are less used.
Pinotsis, Dimitris, Miller, Earl K, Siegel, Markus, Pinotsis, Dimitrios, Miller, Earl   +4 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

The Hidden Brain: Uncovering Previously Overlooked Brain Regions by Employing Novel Preclinical Unbiased Network Approaches

Frontiers in Systems Neuroscience, 2021
A large focus of modern neuroscience has revolved around preselected brain regions of interest based on prior studies. While there are reasons to focus on brain regions implicated in prior work, the result has been a biased assessment of brain function ...
Sierra Simpson, Yueyi Chen, Yueyi Chen, Emma Wellmeyer, Lauren C. Smith, Brianna Aragon Montes, Olivier George, Adam Kimbrough, Adam Kimbrough, Adam Kimbrough   +9 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Toward stressor-free stress estimation: The integrated information theory explains the information dynamics of stress

iScience
Summary: Recent neurological studies have revealed several detailed stress mechanisms. However, the latent variables behind stress study still interpret stress responses as difficult.
Takayuki Niizato, Yuta Nishiyama, Yuta Oka, Poe Thinzar Aung, Shusaku Nomura   +4 more
doaj   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Visualizing and quantifying movement from pre-recorded videos: The spectral time-lapse (STL) algorithm [v1; ref status: indexed, http://f1000r.es/2qo]

F1000Research, 2014
When studying animal behaviour within an open environment, movement-related data are often important for behavioural analyses. Therefore, simple and efficient techniques are needed to present and analyze the data of such movements.
Christopher R Madan, Marcia L Spetch
doaj   +1 more source